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Cholesteryl myristate

CAS No.
1989-52-2
Chemical Name:
Cholesteryl myristate
Synonyms
CM;C14:0 CE;tetradecanoate;Cholestryl myristate;CHOLESTERYL MYRISTATE;CHOLESTEROL MYRISTATE;Cholestryl myristic acid;Cholesterol Myristate >Cholesterol=tetradecanoate;CHOLESTERYL TETRADECANOATE
CBNumber:
CB4280873
Molecular Formula:
C41H72O2
Molecular Weight:
597.01
MDL Number:
MFCD00014256
MOL File:
1989-52-2.mol
Last updated:2023-05-25 18:01:08

Cholesteryl myristate Properties

Melting point 84 °C
Boiling point 589.77°C (rough estimate)
Density 0.9309 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. Sealed in dry,2-8°C
solubility Chloroform (Slightly), Hexanes (Slightly)
form A crystalline solid
LogP 16.656 (est)
CAS DataBase Reference 1989-52-2(CAS DataBase Reference)
NIST Chemistry Reference Cholesteryl myristate(1989-52-2)
EPA Substance Registry System Cholest-5-en-3-ol (3.beta.)-, tetradecanoate (1989-52-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

Cholesteryl myristate price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S455342 CHOLESTERYL MYRISTATE Aldrich 1989-52-2 250mg $179 2024-03-01 Buy
Cayman Chemical 26439 Cholesteryl Myristate 1989-52-2 500mg $32 2024-03-01 Buy
Cayman Chemical 26439 Cholesteryl Myristate 1989-52-2 1g $61 2024-03-01 Buy
Biosynth Carbosynth FC61972 Cholesterol Myristate 1989-52-2 10g $62.5 2021-12-16 Buy
ChemScene CS-6327 Cholesterolmyristate ≥98.0% 1989-52-2 250mg $72 2021-12-16 Buy
Product number Packaging Price Buy
S455342 250mg $179 Buy
26439 500mg $32 Buy
26439 1g $61 Buy
FC61972 10g $62.5 Buy
CS-6327 250mg $72 Buy

Cholesteryl myristate Chemical Properties,Uses,Production

Description

Cholesteryl myristate is a cholesterol ester. Levels of cholesteryl myristate are increased in the serum, liver, and aorta in rabbits fed a high-cholesterol diet and positively correlate with development of non-alcoholic fatty liver disease (NAFLD). Plasma levels of cholesteryl myristate also positively correlate with the presence of unstable atherosclerotic plaques in coronary artery disease. Cholesterol myristate has been used in the composition of lipid nanoparticles as drug carrier systems for drugs with low water solubility.

Uses

Cholesteryl Myristate is a natural steroid present in traditional Chinese medicine or used in tribal medicine.

Definition

ChEBI: A cholesterol ester obtained by the formal condensation of the hydroxy group of cholesterol with the carboxy group of myristic acid.

Purification Methods

Crystallise the myristate ester from Me2CO, EtOH/EtOAc or EtOH/Et2O or n-pentanol. Purify it also by column chromatography on silica gel and eluting with MeOH then evaporating to dryness. Recrystallise it and finally, dry it in vacuo over P2O5 and store it at -20o. [Labarière et al. Analyt Chem 30 1466 1958, Malanik & Malat Anal Chim Acta 76 464 1975, Beilstein 6 III 2638].

Cholesteryl myristate Preparation Products And Raw materials

Raw materials

Preparation Products

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3β-Hydroxy-5-cholestene 3-tetradecanoate, 5-Cholesten-3β-ol 3-tetradecanoate, Cholesteryl tetradecanoate Cholest-5-en-3β-ol tetradecanoate Cholesterol=tetradecanoate Myristic acid 3β-cholesteryl ester Tetradecanoic acid 3β-cholesteryl ester Cholesteryl myristate,97%,liquid crystal MYRISTIC ACID CHOLESTEROL ESTER (3β)-cholest-5-en-3-yltetradecanoate 3β-tetradecanoyloxycholest-5-ene Cholest-5-en-3-ol (3beta)-, tetradecanoate Cholest-5-en-3-yl myristate Cholestryl myristate CM tetradecanoate CHOLESTERYL MYRISTATE (TETRADECANOATE) CHOLESTERYL MYRISTATE, LIQUID CRYSTAL 99% CHOLESTERYL TETRADECANOATE CHOLESTERYL TETRADODEDECANOATE CHOLESTERYL MYRISTATE Cholest-5-en-3beta-yl myristate CHOLESTEROL MYRISTATE 3BETA-HYDROXY-5-CHOLESTENE 3-TETRADECANOATE [(3s,8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthren-3-yl] tetradecanoate 5-CHOLESTEN-3-BETA-OL MYRISTATE 5-CHOLESTEN-3BETA-OL 3-TETRADECANOATE 5-Cholesten-3β-ol 3-tetradecanoate 3β-hydroxy-5-cholestene 3-tetradecanoate Cholestryl myristic acid Cholesteryl Tetradecanoate (Myristate) Cholesteryl myristate, liquid crystal, 97% Cholesterol Myristate > Cholest-5-en-3-ol (3β)-, 3-tetradecanoate C14:0 CE (3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl tetradecanoate Cholest-5-en-3-ol (3β)-, 3-tetradecanoate Cholesterol myristate, >98% Potassium Channel,inhibit,Endogenous Metabolite,Inhibitor,Nicotinic acetylcholine receptors,nAChR,Gamma-aminobutyric acid Receptor,γ-Aminobutyric acid Receptor,Cholesterol myristate,GABA Receptor,KcsA 5-CHOLESTEN-3β-OL MYRISTATE 1989-52-2 C41H74O2 C41H72O2 BioChemical Biochemicals and Reagents Cholesterol and Derivatives Lipids Sterols Steroids Cholesteryl Compounds (Liquid Crystals) Functional Materials Liquid Crystals & Related Compounds