Exendin-4 (Acetate)
- CAS No.
- 914454-01-6
- Chemical Name:
- Exendin-4 (Acetate)
- Synonyms
- Exendin-4 (Acetate);Exendin-4 (48-86) amide (acetate);Exenatide acetate (Exendin-4 acetate);Exendin-4 Acetate,Exenatide acetate, >98%;Exenatide,Exendin 4 acetate,Glucagon Receptor,Exendin-4,inhibit,Exendin4 acetate,Exendin 4,Exendin4,GCGR,Inhibitor
- CBNumber:
- CB43048652
- Molecular Formula:
- C186H285N50O62RS
- Molecular Weight:
- 4245.62
- MDL Number:
- MOL File:
- 914454-01-6.mol
Exendin-4 (Acetate) price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 11096 | Exendin-4 (acetate) ≥95% | 914454-01-6 | 500μg | $101 | 2024-03-01 | Buy |
| Cayman Chemical | 11096 | Exendin-4 (acetate) ≥95% | 914454-01-6 | 1mg | $162 | 2024-03-01 | Buy |
| Cayman Chemical | 11096 | Exendin-4 (acetate) ≥95% | 914454-01-6 | 5mg | $379 | 2024-03-01 | Buy |
| ChemScene | CS-5100 | Exendin-4acetate 99.44% | 914454-01-6 | 5mg | $168 | 2021-12-16 | Buy |
| ChemScene | CS-5100 | Exendin-4acetate 99.44% | 914454-01-6 | 10mg | $252 | 2021-12-16 | Buy |
Exendin-4 (Acetate) Chemical Properties,Uses,Production
Description
Exendin-4 (48-86) amide is a 39-amino acid peptide fragment corresponding to residues 48-86 of exendin-4, a peptide produced in the salivary gland of the Gila monster, and an agonist of the glucagon-like peptide 1 receptor (GLP-1R; IC50 = 3.5 nM).1,2 Radiolabeled exendin-4 (48-86) amide localizes to the pancreas, kidneys, and bladder in a porcine model of diabetes induced by streptozotocin .3 Exendin-4 (48-86) amide (10 nmol/kg) improves motor performance in the rotarod test in an mouse model of Parkinson’s disease induced by MPTP.4 It reduces MPTP-induced loss of dopaminergic neurons in the substantia nigra in the same model. Formulations containing exendin-4 (48-86) amide have been used in the treatment of type 2 diabetes mellitus.
References
1. Clardy, S.M., Mohan, J.F., Vinegoni, C., et al. Rapid, high efficiency isolation of pancreatic β-
2. Doyle, M.E., Theodorakis, M.J., Holloway, H.W., et al. The importance of the nine-
3. Nalin, L., Selvaraju, R.K., Velikyan, I., et al. Positron emission tomography imaging of the glucagon-
4. Zhang, L., Zhang, L., Li, Y., et al. The novel dual GLP-
Exendin-4 (Acetate) Preparation Products And Raw materials
Raw materials
Preparation Products
Exendin-4 (Acetate) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6347 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| DC Chemicals | 021-58447131 13564518121 | sales@dcchemicals.com | China | 9414 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Supplier | Advantage |
|---|---|
| InvivoChem | 58 |
| TargetMol Chemicals Inc. | 58 |
| Aladdin Scientific | 58 |
| Haoyuan Chemexpress Co., Ltd. | 61 |
| MedChemexpress LLC | 58 |
| Musechem | 60 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 58 |
| DC Chemicals | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |