ChemicalBook >> CAS DataBase List >>VZRIHFZJVIOJBE-UHFFFAOYSA-N
VZRIHFZJVIOJBE-UHFFFAOYSA-N
- CAS No.
- 1240494-13-6
- Chemical Name:
- VZRIHFZJVIOJBE-UHFFFAOYSA-N
- Synonyms
- VZRIHFZJVIOJBE-UHFFFAOYSA-N;Boronic acid, B-[2-[[[5-[[(4-fluorophenyl)amino]carbonyl]-2-pyridinyl]thio]methyl]phenyl]-
- CBNumber:
- CB43396221
- Molecular Formula:
- C19H16BFN2O3S
- Molecular Weight:
- 382.22
- MDL Number:
- MFCD28963933
- MOL File:
- 1240494-13-6.mol
Last updated:2023-05-09 09:30:42
| Density | 1.39±0.1 g/cm3(Predicted) |
|---|---|
| pka | 8.45±0.53(Predicted) |
| FDA UNII | 36UH926WTQ |
VZRIHFZJVIOJBE-UHFFFAOYSA-N Chemical Properties,Uses,Production
Description
SX-517 is a potent noncompetitive boronic acid CXCR1/2 antagonist. SX-517 inhibited CXCL1-induced Ca(2+) flux (IC50 = 38 nM) in human PMNs but had no effect on the Ca(2+) flux induced by C5a, fMLF, or PAF. SX-517 is the first reported boronic acid chemokine antagonist and represents a novel pharmacophore for CXCR1/2 antagonism.
VZRIHFZJVIOJBE-UHFFFAOYSA-N Preparation Products And Raw materials
VZRIHFZJVIOJBE-UHFFFAOYSA-N Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24018 | 58 |
| Supplier | Advantage |
|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
VZRIHFZJVIOJBE-UHFFFAOYSA-N
Boronic acid, B-[2-[[[5-[[(4-fluorophenyl)amino]carbonyl]-2-pyridinyl]thio]methyl]phenyl]-
1240494-13-6