Triazavirin
- CAS No.
- 928659-17-0
- Chemical Name:
- Triazavirin
- Synonyms
- Triazavirin;Triazavirin (Riamilovir);Triazavirin sodium hydrate (TZV, Riamilovir);Sodium 2-methylthio-6-nitro-1,2,4-triazol [5,1c][1,2,3]-triazin-7-one dihydrate;Sodium 7-(methylthio)-3-nitro-4-oxo-4H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-6-ide dihydrate;1,2,4]Triazolo[5,1-c][1,2,4]triazin-4(6H)-one, 7-(methylthio)-3-nitro-, sodium salt, hydrate;Inhibitor,DNA,influenza,transmission,encephalitis,antiviral,RNA,Triazavirin,DNA/RNA Synthesis,Nucleoside Antimetabolite/Analog,Tick-born,Influenza Virus,nucleoside,replication,inhibit
- CBNumber:
- CB44763419
- Molecular Formula:
- C5H7N6NaO4S
- Molecular Weight:
- 270.2
- MDL Number:
- MOL File:
- 928659-17-0.mol
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
|---|---|
| solubility | DMSO: 125 mg/mL (436.76 mM) |
| form | A solid |
| FDA UNII | G1JE34QF2S |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
Triazavirin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0016556 | Triazavirin 99.01% | 928659-17-0 | 5mg | $75 | 2021-12-16 | Buy |
| ChemScene | CS-0016556 | Triazavirin 99.01% | 928659-17-0 | 10mg | $125 | 2021-12-16 | Buy |
| ChemScene | CS-0016556 | Triazavirin 99.01% | 928659-17-0 | 50mg | $350 | 2021-12-16 | Buy |
| DC Chemicals | DC21567 | Triazavirin(Riamilovir) >98% | 928659-17-0 | 100mg | $600 | 2021-12-16 | Buy |
| Ambeed | A1228484 | Sodium7-(methylthio)-3-nitro-4-oxo-4H-[1,2,4]triazolo[5,1-c][1,2,4]triazin-6-idedihydrate 99+% | 928659-17-0 | 10mg | $116 | 2021-12-16 | Buy |
Triazavirin Chemical Properties,Uses,Production
Biological Activity
Triazavirin (TZV, Riamilovir) is a novel antiviral drug, a nucleoside analogue of nucleic acid, which inhibits the synthesis of viral RNA and DNA and the replication of genomic fragments. It is active against influenza and many other viruses, and acts as an effective protective agent during influenza transmission.
in vitro
The efficacy of Triazavirin against the tick-borne encephalitis virus is estimated in the sensitive cell culture. In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain < i> Sofiin ) by accumulation in the SKEV cell culture.
in vivo
The therapeutic efficacy Triazavirin against experimental Forest-Spring encephalitis on albino mice is studied. The results shows that in high doses (200-400 mg/kg) Triazavirin moderately protects the infected animals. A significant increase of the animal lifespan in the test groups (from 4.1 to 4.8 days) and a statistically valid decrease of the virus accumulation in the target organ are observed.
target
Nucleoside analogue; Influenza virus
Triazavirin Preparation Products And Raw materials
Raw materials
Preparation Products
Triazavirin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10247 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9976 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Changzhou AniKare Pharmatech Co., Ltd. | +86-0519-8359-8696 +8618018249389 | sales@anikare.com | China | 8472 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |