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L-CYSTEINESULFINIC ACID MONOHYDRATE

CAS No.
207121-48-0
Chemical Name:
L-CYSTEINESULFINIC ACID MONOHYDRATE
Synonyms
3-sulfino-l-alanine;Sulfino-L-alanine hydrate;L-Cysteinesulfinic Acid (hydrate);(2R)-2-aMino-3-sulfinopropanoic acid;L-Cysteinesulfinic acid Monohydrate 99%;(1R)-1-amino-2-mercaptoethanesulfinic acid hydrate;L Cysteinesulfinic acid monohydrate,LCysteinesulfinic acid monohydrate,Metabotropic glutamate receptors,Inhibitor,L-Cysteinesulfinic acid,inhibit,mGluR
CBNumber:
CB4503615
Molecular Formula:
HO2SCH2CH(NH2)CO2HH2O
Molecular Weight:
171.17
MDL Number:
MFCD00150732
MOL File:
207121-48-0.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:19

L-CYSTEINESULFINIC ACID MONOHYDRATE Properties

Melting point 163 °C (dec.)(lit.)
storage temp. -20°C
solubility Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
optical activity [α]25/D +24°, c = 1 in 1 M HCl
Stability Temperature Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  2930901300

L-CYSTEINESULFINIC ACID MONOHYDRATE price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 270881 L-Cysteinesulfinic acid monohydrate 99% 207121-48-0 1g $796 2024-03-01 Buy
Sigma-Aldrich 270881 L-Cysteinesulfinic acid monohydrate 99% 207121-48-0 250mg $201 2023-06-20 Buy
Cayman Chemical 29597 L-Cysteinesulfinic Acid (hydrate) 207121-48-0 50mg $61 2024-03-01 Buy
Cayman Chemical 29597 L-Cysteinesulfinic Acid (hydrate) 207121-48-0 100mg $111 2024-03-01 Buy
Sigma-Aldrich C4418 L-Cysteinesulfinic acid monohydrate 207121-48-0 100mg $134 2024-03-01 Buy
Product number Packaging Price Buy
270881 1g $796 Buy
270881 250mg $201 Buy
29597 50mg $61 Buy
29597 100mg $111 Buy
C4418 100mg $134 Buy

L-CYSTEINESULFINIC ACID MONOHYDRATE Chemical Properties,Uses,Production

Description

L-Cysteinesulfinic acid is an excitatory amino acid and agonist of metabotropic glutamate receptors (mGluRs). It increases intracellular inositol phosphate levels in CHO cells expressing mGluR1, mGluR5, or mGluR8 (EC50s = 120, 30, and 110 μM, respectively) and inhibits forskolin-induced cAMP production in CHO cells expressing mGluR2 or mGluR6 and hamster kidney cells expressing mGluR4 (EC50s = 100, 100, and 2,000 μM, respectively). It selectively binds to mGluR1α (Ki = 3,510 nM) over adrenergic, dopamine, histamine, muscarinic, nicotinic, or serotonin receptors (Kis = >10,000 nM for all). L-Cysteinesulfinic acid (1 mM) decreases mean arterial blood pressure and heart rate in rats when microinjected into the nucleus tractus solitarius (NTS). L-Cysteinesulfinic acid can be formed via oxidation of L-cysteine by reactive oxygen species (ROS), and conversion of cysteine to L-cysteinesulfinic acid in cysteine-containing peptide probes has been used to measure oxidative stress.

Chemical Properties

Off-White Solid

Uses

L-Cysteinesulfinic acid monohydrate has been used in the fluorescence measurement of cysteine oxidation.

Uses

An amino acid derivative with neuropathological interest; Putative excitatory amino acid neurotransmitter.

Biochem/physiol Actions

Cysteinesulfinic acid (CSA), also called 3-sulfinoalanine is synthesized by the conversion of sulfur to sulfinic acid in cysteine by the enzyme cysteine dioxygenase (CDO). CSA is a putative excitatory amino acid (EAA) with neurotransmitter functionality. It also regulates cardiovascular functions.

L-CYSTEINESULFINIC ACID MONOHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

L-CYSTEINESULFINIC ACID MONOHYDRATE Suppliers

Global( 48)Suppliers
Supplier Tel Email Country ProdList Advantage
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12740 58
Hong Kong Tiansheng New Material Trading Co., Ltd
+8617320695765 zxx@hktiansheng.com China 981 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94838 76
Energy Chemical 021-021-58432009 400-005-6266 sales8178@energy-chemical.com China 44700 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Syntechem Co.,Ltd info@syntechem.com China 12990 57
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 27322 60

View Lastest Price from L-CYSTEINESULFINIC ACID MONOHYDRATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Cysteinesulfinic acid monohydrate pictures 2022-02-25 L-Cysteinesulfinic acid monohydrate
207121-48-0
US $1.90 / g 1Kg/Bag 99% 19tons Hong Kong Tiansheng New Material Trading Co., Ltd

207121-48-0(L-CYSTEINESULFINIC ACID MONOHYDRATE)Related Search:

(2R)-2-aMino-3-sulfinopropanoic acid L-Cysteinesulfinic acid Monohydrate 99% 3-sulfino-l-alanine (1R)-1-amino-2-mercaptoethanesulfinic acid hydrate L-Cysteinesulfinic Acid (hydrate) Sulfino-L-alanine hydrate L Cysteinesulfinic acid monohydrate,LCysteinesulfinic acid monohydrate,Metabotropic glutamate receptors,Inhibitor,L-Cysteinesulfinic acid,inhibit,mGluR 207121-48-0 HO2SCH2CHNH2CO2HH2O Amino Acids & Derivatives Sulfur & Selenium Compounds