ChemicalBook >> CAS DataBase List >>Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-

CAS No.
858557-69-4
Chemical Name:
Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
Synonyms
MUN57694;26S proteasome inhibitor I;Proteasome,Inhibitor,inhibit,MUN57694,MUN-57694;(2,6-Dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone;Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-
CBNumber:
CB48378592
Molecular Formula:
C23H25N3O4
Molecular Weight:
407.46
MDL Number:
MOL File:
858557-69-4.mol
Last updated:2023-09-20 16:43:00

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Properties

Boiling point 621.2±65.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
storage temp. 4°C, protect from light
solubility DMSO : 31.25 mg/mL (76.69 mM; ultrasonic and warming and heat to 60°C)
pka -0.58±0.44(Predicted)

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Chemical Properties,Uses,Production

Biological Activity

20S Proteasome-IN-1 is a 26S proteasome inhibitor extracted from patent WO2006128196A2 compound 2. 20S Proteasome-IN-1 has the potential for cancer, immune-related disorders, inflammation, ischemic conditions, neurodegenerative disorders and other diseases research[1].

References

[1]. Parlati F, et, al. Novel substrate for rpn 11 enzymatic activity. WO2006128196A2.

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Suppliers

Global( 16)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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Shenzhen Shengda Pharma Limited
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InvivoChem
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TargetMol Chemicals Inc.
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Aladdin Scientific
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Rayge(SuZhou)New Materials Co.,Ltd 0512-87813132-801 13913535368 3043369320@qq.com China 94 65
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9767 58
Shanghai Dongyang Biotechnology Co., Ltd. 0512-0512-13601744364 13601744364 chemsharker@126.com China 879 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
Shenzhen Shengda Pharmaceutical co Limited 0755-85269922 13424394241 sales@shengdapharm.com China 506 58

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- Spectrum

Methanone, (2,6-dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]- MUN57694 26S proteasome inhibitor I Proteasome,Inhibitor,inhibit,MUN57694,MUN-57694 (2,6-Dimethoxyphenyl)[4-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone 858557-69-4