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ChemicalBook >> CAS DataBase List >>Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)-

Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)-

Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- Structure
Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- structure
CAS No.
2242582-40-5
Chemical Name:
Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)-
Synonyms
CMPD-39;USP30 inhibitor 18;DUBs,Mitophagy,USP30,Deubiquitinase,USP30 inhibitor 18,Inhibitor,Parkin,USP-30 inhibitor 18,inhibit;Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)-
CBNumber:
CB49760266
Molecular Formula:
C26H28FN3O4S
Molecular Weight:
497.59
MDL Number:
MOL File:
2242582-40-5.mol
Last updated:2023-09-04 15:51:00
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Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- Properties

Density 1.278±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
pka 12.09±0.50(Predicted)

Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- Chemical Properties,Uses,Production

Biological Activity

USP30 inhibitor 18 is a selective USP30 inhibitor with an IC50 of 0.02 μM. USP30 inhibitor 18 increases protein ubiquitination and accelerates mitophagy[1].

References

[1]. Arthur F Kluge, et al. Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy. Bioorg Med Chem Lett. 2018 Aug 15;28(15):2655-2659.

Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- Preparation Products And Raw materials

Raw materials

Preparation Products

Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- Suppliers

Global( 6)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 021-59167510 18117107507 vip@med-life.cn China 5019 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9180 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 12007 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
TargetMol Chemicals Inc. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
RD International Technology Co., Limited 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- Spectrum

Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)-(2242582-40-5)1HNMR
Benzenepropanamide, N-[4-[[(1,1-dimethylethyl)amino]sulfonyl]phenyl]-α-[(4-fluorobenzoyl)amino]-, (αS)- USP30 inhibitor 18 DUBs,Mitophagy,USP30,Deubiquitinase,USP30 inhibitor 18,Inhibitor,Parkin,USP-30 inhibitor 18,inhibit CMPD-39 2242582-40-5