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4-Hydroxyphenethyl alcohol

CAS No.
501-94-0
Chemical Name:
4-Hydroxyphenethyl alcohol
Synonyms
TYROSOL;4-(2-HYDROXYETHYL)PHENOL;Benzeneethanol, 4-hydroxy-;2-(4-HYDROXYPHENYL)ETHANOL;4-Hydroxyphenylethanol;P-HYDROXYPHENYLETHANOL;p-Hydroxyphenylethyl alcohol;4-Hydroxyphenyl-2-ethanol;PHEP;p-Tyrosol
CBNumber:
CB5227235
Molecular Formula:
C8H10O2
Molecular Weight:
138.16
MDL Number:
MFCD00002902
MOL File:
501-94-0.mol
MSDS File:
SDS
Last updated:2024-04-23 16:18:34

4-Hydroxyphenethyl alcohol Properties

Melting point 89-92 °C(lit.)
Boiling point 195°C (18 mmHg)
Density 1.0742 (rough estimate)
refractive index 1.5590 (estimate)
Flash point 139°C/1mm
storage temp. Store below +30°C.
solubility 124g/l
form Crystals or Crystalline Powder
pka 10.17±0.13(Predicted)
color Off-white to light beige
Odor at 100.00 %. mild sweet floral fruity
Odor Type floral
Water Solubility slightly soluble
BRN 1859884
InChIKey YCCILVSKPBXVIP-UHFFFAOYSA-N
LogP 0.851 (est)
CAS DataBase Reference 501-94-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 1AK4MU3SNX
NIST Chemistry Reference Benzeneethanol, 4-hydroxy-(501-94-0)
EPA Substance Registry System 4-Hydroxybenzeneethanol (501-94-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25-36
WGK Germany  3
10
Hazard Note  Irritant
TSCA  Yes
HS Code  29072900
NFPA 704
1
2 0

4-Hydroxyphenethyl alcohol price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL80166 Tyrosol phyproof? Reference Substance 501-94-0 20MG $356 2024-03-01 Buy
Sigma-Aldrich 79058 2-(4-Hydroxyphenyl)ethanol analytical standard 501-94-0 100mg $28.6 2024-03-01 Buy
Sigma-Aldrich 79058 2-(4-Hydroxyphenyl)ethanol analytical standard 501-94-0 500mg $95 2024-03-01 Buy
Sigma-Aldrich 188255 2-(4-Hydroxyphenyl)ethanol 98% 501-94-0 5g $106 2024-03-01 Buy
Sigma-Aldrich 188255 2-(4-Hydroxyphenyl)ethanol 98% 501-94-0 25g $109 2024-03-01 Buy
Product number Packaging Price Buy
PHL80166 20MG $356 Buy
79058 100mg $28.6 Buy
79058 500mg $95 Buy
188255 5g $106 Buy
188255 25g $109 Buy

4-Hydroxyphenethyl alcohol Chemical Properties,Uses,Production

Description

Phenylalanine is an amino acid, which are the building blocks of proteins in your body. This molecule exists in two forms or arrangements: L-phenylalanine and D-phenylalanine. They’re nearly identical but have a slightly different molecular structure. The L-form is found in foods and used to produce proteins in your body, while the D-form can be synthesized for use in certain medical applications . Your body is unable to produce enough L-phenylalanine on its own, so it’s considered an essential amino acid that must be obtained through your diet. It’s found in a wide variety of foods — both plant and animal sources. In addition to its role in protein production, phenylalanine is used to make other important molecules in your body, several of which send signals between different parts of your body. Phenylalanine has been studied as a treatment for several medical conditions, including skin disorders, depression and pain. However, it can be dangerous for people with the genetic disorder phenylketonuria (PKU).

Health Benefits

Phenylalanine can be used to produce the molecule dopamine. Dopamine malfunction in the brain is associated with some forms of depression . One small 12-person study showed a possible benefit of a mixture of the D- and L-forms of this amino acid for treating depression, with 2/3 of patients showing improvement . However, there is minimal other support for phenylalanine’s effects on depression, and most studies have not found clear benefits. In addition to vitiligo and depression, phenylalanine has been studied for potential effects on:

Pain: The D-form of phenylalanine may contribute to pain relief in some instances, though study results are mixed .

Alcohol withdrawal: A small amount of research indicates that this amino acid, along with other amino acids, may help alleviate symptoms of alcohol withdrawal.

Parkinson’s disease: Very limited evidence suggests that phenylalanine may be beneficial in treating Parkinson’s disease, but more studies are needed .

ADHD: Currently, research does not indicate benefits of this amino acid for the treatment of attention deficit hyperactivity disorder (ADHD) .

Side effects

Phenylalanine is found in many protein-containing foods and is “generally recognized as safe” by the Food and Drug Administration (FDA) (27). The amount of this amino acid found in foods should not pose a risk for otherwise healthy individuals. What’s more, few or no side effects are generally observed at supplement doses of 23–45 mg per pound (50–100 mg per kg) of body weight (9Trusted Source, 13Trusted Source). However, it may be best for pregnant women to avoid taking phenylalanine supplements.

Uses

L-phenylalanine (LPA) serves as a building block for the various proteins that are produced in the body. LPA can be converted to L-tyrosine (another amino acid ) and subsequently to L-dopa, norepinephrine, and epinephrine . LPA can also be converted (through a separate pathway) to phenylethylamine, a substance that occurs naturally in the brain and appears to elevate mood.

Chemical Properties

off-white to light beige crystals or crystalline

Uses

Tyrosol (Metoprolol EP Impurity G) is a phenolic antioxidant.

Uses

Phenolic antioxidant.

Definition

ChEBI: A phenol substituted at position 4 by a 2-hydroxyethyl group.

General Description

2-(4-Hydroxyphenyl)ethanol is a phenolic alcohol commonly present in olive mill wastewater.

Biochem/physiol Actions

Antioxidant found in olive oil.

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View Lastest Price from 4-Hydroxyphenethyl alcohol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxyphenyl ethanol pictures 2024-04-23 4-Hydroxyphenyl ethanol
501-94-0
US $10.00 / kg 1kg 99.7% 200000kg Ouhuang Engineering Materials (Hubei) Co., Ltd
4-Hydroxyphenyl ethanol pictures 2023-08-16 4-Hydroxyphenyl ethanol
501-94-0
US $499.00 / KG 1KG >99% 50000kg/Month Weijer International Trade (Hebei) Co., Ltd
4-Hydroxyphenethyl alcohol pictures 2023-08-09 4-Hydroxyphenethyl alcohol
501-94-0
US $0.00-0.00 / kg 1kg 0.99 50000kg Hebei Kingfiner Technology Development Co.Ltd
Tyrosol (antioxidant): 4-(2-hydroxyethyl)phenol P-HYDROXY PHENETHYL ALCOHOL 2-(4-Hydroxyphenyl)ethanol(p-HPEA) Para Hydroxy Phenethyl Alcohol 2-(4-Hydroxyphenyl)ethanol 98% PARA-TYROSOL 2-(4-HYDROXYPHENYL)ETHAN-1-OL PARA-(2-HYDROXYETHYL)PHENOL 2-(4-Hydroxyphenyl)ethanol98% 4-hydroxy-Benzeneethand 4-Hydroxyphenethyl alcohol 98% 4-Hydroxyphenethyl alcohol,98% 2-(4-Hydroxyphenyl)ethal 2-(4-Hydroxyphenyl)ethanol,4-Hydroxyphenethyl alcohol, Tyrosol 4-Hydroxyphenethyl a 4-Hydroxyphenethyl alcohol, Tyrosol NSC 59876 4-hydroxy-benzeneethano 4-hydroxy-Benzeneethanol beta-(4-Hydroxyphenyl)ethanol beta-(p-Hydroxyphenyl)ethanol Ethanol, 2-(4-hydroxyphenyl) Phenethyl alcohol, p-hydroxy- p-Hydroxy-benzeneethanol p-hydroxyphenylethylalkohol p-Thyrosol tyrosol [2-(4-hydroxy-phenyl)ethanol] 2-(P-HYDROXYPHENYL)ETHANOL 2-(4-HYDROXYPHENYL)ETHYL ALCOHOL 4-HEP/4-2(2-Hydroxyethyl)-phenol 4-Hydroxybenzeneethanol, 9CI Salidrosol 4-HYDROXYPHENETHYL ALCOHOL 4-HYDROXYPHENYLETHYL ALCOHOL AKOS 91052 4-(2-Hydroxyethyl)phenol 4-Hydroxyphenethyl Alcohol 2-(4-Hydroxyphenyl)ethyl Alcohol p-HPEA Metoprolol Tartrate EP IMpurity-E Metoprolol Tartrate EP IMpurity-G Metoprolol EP IMpurity G 4-(2-Hydroxyethyl)phenol 98% 4-Hydroxyphenethyl alcohol, 2-(4-Hydroxyphenyl)ethan-1-ol The hydroxy benzene ethanol Tyrosol (Metoprolol Impurity) Tyrosol (Betaxolol Impurity 1) 2-(4-HYDROXYPHENYL)ETHANOL FOR SYNTHESIS Betaxolol Impurity 1 (Tyrosol) 2-(4-Hydroxyphenyl)ethanol> 4-Hydroxyphenethyl alcohol 2-(4-Hydroxyphenyl)ethanol Tyrosol 4-(2-Hydroxyethyl)phenol 4-(2-HYDROXYETHYL) PHENOL Para Hydroxy Phenethyl Alcohol H**2-(4-Hydroxyphenyl)ethanol Metoprolol-7 2-(4-hydroxyphenyl)ethanol 501-94-0 Metoprolol Impurity 7(Metoprolol EP Impurity G) Hydroxyphenethyl alcohol Metoprolol Impurity G Tyramol 4-Hydroxyphenyl-2-ethanol PHEP