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TM38837

CAS No.
1253641-65-4
Chemical Name:
TM38837
Synonyms
TM38837;peripheral,Cannabinoid Receptor,TM-38837,CB1,antiobesity,TM38837,inhibit,fat,TM 38837,Inhibitor,metabolic,fear;1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-4-ethyl-N-1-piperidinyl-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]-
CBNumber:
CB53054760
Molecular Formula:
C30H25Cl2F3N4OS
Molecular Weight:
617.51
MDL Number:
MFCD26406003
MOL File:
1253641-65-4.mol
Last updated:2024-04-24 17:21:45

TM38837 Properties

Melting point 171-172 °C
Density 1.38±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 41.67 mg/mL (67.48 mM)
pka 11.17±0.20(Predicted)

TM38837 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 7131 TM38837 ≥98%(HPLC) 1253641-65-4 5 $209 2021-12-16 Buy
ChemScene CS-0045262 TM38837 99.61% 1253641-65-4 50mg $550 2021-12-16 Buy
ChemScene CS-0045262 TM38837 99.61% 1253641-65-4 100mg $950 2021-12-16 Buy
ChemScene CS-0045262 TM38837 99.61% 1253641-65-4 5mg $150 2021-12-16 Buy
ChemScene CS-0045262 TM38837 99.61% 1253641-65-4 10mg $200 2021-12-16 Buy
Product number Packaging Price Buy
7131 5 $209 Buy
CS-0045262 50mg $550 Buy
CS-0045262 100mg $950 Buy
CS-0045262 5mg $150 Buy
CS-0045262 10mg $200 Buy

TM38837 Chemical Properties,Uses,Production

Biological Activity

TM38837 is a peripherally selective cannabinoid receptor type 1 (CB1) receptor antagonist. It has limited brain penetration to minimize or prevent CNS adverse effects and retain potential anti-obesity effects. Also it can reduces the propensity for psychotic side effects.

in vivo

TM38837 (10-100 mg/kg; po) induces a significant increase in freezing behavior at 100 mg/kg.

< td class="col2"> 7-8 weeks old male C57BL/6 N mice (B6N)
Animal Model:
Dosage: 10, 30, or 100 mg/kg
Administration: po < /td>
Result: High dose (100 mg/kg) induced a significant increase in freezing behavior. < /td>

target

CB1

storage

Store at -20°C

TM38837 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 26)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 18224 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2923 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 27322 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9754 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720 chaolaichem@foxmail.com China 9038 58
Shanghai Biopharmaleader Co., Ltd. +86 18721201413 sales@biopharmaleader.com China 1720 58

View Lastest Price from TM38837 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TM-38837 pictures 2024-04-24 TM-38837
1253641-65-4
US $8.00-2.00 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
  • TM-38837 pictures
  • TM-38837
    1253641-65-4
  • US $8.00-2.00 / kg
  • 99%
  • Henan Fengda Chemical Co., Ltd
TM38837 peripheral,Cannabinoid Receptor,TM-38837,CB1,antiobesity,TM38837,inhibit,fat,TM 38837,Inhibitor,metabolic,fear 1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-4-ethyl-N-1-piperidinyl-5-[5-[2-[4-(trifluoromethyl)phenyl]ethynyl]-2-thienyl]- 1253641-65-4