BocNH-PEG7-OH
- CAS No.
- 1292268-13-3
- Chemical Name:
- BocNH-PEG7-OH
- Synonyms
- tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate;NHBoc-PEG7-OH;BocNH-PEG7-OH;BocNH-PEG7-alcohol;N-Boc-PEG7-alcohol N-Boc-;t-boc-N-amido-PEG7-alcohol;20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol;t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate;5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester;BocNH-PEG7-OH/5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
- CBNumber:
- CB53340579
- Molecular Formula:
- C19H39NO9
- Molecular Weight:
- 425.51
- MDL Number:
- MFCD29049415
- MOL File:
- 1292268-13-3.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
BocNH-PEG7-OH price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| BroadPharm | BP-23546 | N-Boc-PEG7-alcohol 98% | 1292268-13-3 | 500mg | $280 | 2021-12-16 | Buy |
| Activate Scientific | AS104083 | BocNH-PEG7-OH 95+% | 1292268-13-3 | 1g | $615 | 2021-12-16 | Buy |
| purepeg | 432407 | BocNH-PEG7-OH min.95% | 1292268-13-3 | 1g | $350 | 2021-12-16 | Buy |
| purepeg | 432407 | BocNH-PEG7-OH min.95% | 1292268-13-3 | 250mg | $185 | 2021-12-16 | Buy |
| Acrotein | B-0973 | BocNH-PEG7-OH 97% | 1292268-13-3 | 0.25g | $192.5 | 2021-12-16 | Buy |
BocNH-PEG7-OH Chemical Properties,Uses,Production
Description
N-Boc-PEG7-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Biological Activity
N-Boc-PEG7-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. Also it is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
| PEGs
| Alkyl/ether
|
BocNH-PEG7-OH Preparation Products And Raw materials
Raw materials
Preparation Products
BocNH-PEG7-OH Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 9i LLC | +18039569191 | MWan@NiNeiLab.com | United States | 418 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
View Lastest Price from BocNH-PEG7-OH manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-25 | NHBoc-PEG7-OH
1292268-13-3
|
US $0.00 / g | 5g | >98.00% | 5g | Xian confluore Biological Technology Co., Ltd. |
-
- NHBoc-PEG7-OH
1292268-13-3
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.