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Fmoc-Val-Ala-PAB-OH

Fmoc-Val-Ala-PAB-OH Structure
Fmoc-Val-Ala-PAB-OH structure
CAS No.
1394238-91-5
Chemical Name:
Fmoc-Val-Ala-PAB-OH
Synonyms
Fmoc-Val-ala-PAB;(9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;CS-2746;Fmoc-Val-Cit-PABA;Fmoc-Val-Ala-PAB-OH;1-Butanesulfonicacid,6-hydroxy-;9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol;L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;(S)-2-(Fmoc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide
CBNumber:
CB53364144
Molecular Formula:
C30H33N3O5
Molecular Weight:
515.6
MDL Number:
MFCD28557282
MOL File:
1394238-91-5.mol
Last updated:2024-03-29 18:52:01
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Fmoc-Val-Ala-PAB-OH Properties

Melting point 218 °C(dec.)
Boiling point 811.1±65.0 °C(Predicted)
Density 1.251±0.06 g/cm3(Predicted)
solubility DMSO : 33.33 mg/mL (64.64 mM; ultrasonic and warming and heat to 80°C)
pka 10.63±0.46(Predicted)
form powder to crystal
color White to Light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
HS Code  2924.29.7790

Fmoc-Val-Ala-PAB-OH price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical F1278 Fmoc-Val-Ala-PAB-OH 1394238-91-5 250MG $257 2024-03-01 Buy
TRC F861090 Fmoc-Val-Ala-PAB 1394238-91-5 250mg $305 2021-12-16 Buy
TRC F861090 Fmoc-Val-Ala-PAB 1394238-91-5 100mg $155 2021-12-16 Buy
ChemScene CS-0102865 Fmoc-Val-Ala-PAB-OH 1394238-91-5 100mg $508 2021-12-16 Buy
Iris Biotech GmbH ADC1060 Fmoc-Val-Ala-PAB 1394238-91-5 1g $877.5 2021-12-16 Buy
Product number Packaging Price Buy
F1278 250MG $257 Buy
F861090 250mg $305 Buy
F861090 100mg $155 Buy
CS-0102865 100mg $508 Buy
ADC1060 1g $877.5 Buy

Fmoc-Val-Ala-PAB-OH Chemical Properties,Uses,Production

Description

Fmoc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations.

Uses

Fmoc-Val-Ala-PAB is a building block used in the synthesis of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers.

Fmoc-Val-Ala-PAB-OH synthesis

150114-97-9
623-04-1
1394238-91-5
Synthesis of Fmoc-Val-Ala-PAB-OH from Fmoc-Val-Ala-OH and 4-Aminobenzyl alcohol

Fmoc-Val-Ala-PAB-OH Preparation Products And Raw materials

Raw materials

Propanamide, 2-amino-N-[4-(hydroxymethyl)phenyl]-, (2S)- 4-Aminobenzyl alcohol Fmoc-Val-Ala-OH FMOC-L-Valine FMOC-VAL-OSU
9-Fluorenylmethyl chloroformate

1of2

Preparation Products

Fmoc-Val-Ala-PAB-OH Suppliers

Global( 99)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 7154 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034 CHINA 3904 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9634 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Huarong Pharm Co., Ltd. 		571-86758373 +8613588754946 sales@huarongpharm.com CHINA 3149 58
ChemExpress 		+86-021-58950125 info@chemexpress.com China 566 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Jinan Carbotang Biotech Co.,Ltd. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
GL Biochem (Shanghai) Ltd. 		58
GL Biochem(Binhai) Ltd. 		58
Finetech Industry Limited 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
Hangzhou Huarong Pharm Co., Ltd. 		58
ChemExpress 		58
Nextpeptide Inc 		58

View Lastest Price from Fmoc-Val-Ala-PAB-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Fmoc-Val-Ala-PAB pictures 2024-03-29 Fmoc-Val-Ala-PAB
1394238-91-5
 US $0.00 / g 1g >95.00% 1g Xian confluore Biological Technology Co., Ltd.
Fmoc-Val-Ala-PAB-OH pictures 2022-10-14 Fmoc-Val-Ala-PAB-OH
1394238-91-5
 US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
  • Fmoc-Val-Ala-PAB pictures
  • Fmoc-Val-Ala-PAB
    1394238-91-5
  • US $0.00 / g
  • >95.00%
  • Xian confluore Biological Technology Co., Ltd.

1394238-91-5(Fmoc-Val-Ala-PAB-OH)Related Search:

Fmoc-Val-Ala-OH Fmoc-Val-Ala-OSu Calcium hydroxide
CS-2746 Fmoc-Val-Ala-PAB-OH, 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol L-Alaninamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]- Fmoc-Val-Ala-PAB-OH Fmoc-Val-ala-PAB (9H-Fluoren-9-yl)methyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate 1-Butanesulfonicacid,6-hydroxy- Inhibitor,Antibody-drug conjugates linkers,ADC Linkers,Fmoc Val Ala PAB OH,inhibit,FmocValAlaPABOH 9-fluorenylmethyloxycarbonyl-valyl-alanyl-4-aminobenzylalcohol Fmoc-Val-Cit-PABA (S)-2-(Fmoc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide 1394238-91-5 Linker ADCs Linkers ADCs ADC LINKER ADC-Linker