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ARG-LYS-GLU-VAL-TYR ACETATE SALT

CAS No.
105184-37-0
Chemical Name:
ARG-LYS-GLU-VAL-TYR ACETATE SALT
Synonyms
SP-5 ACETATE SALT;Splenopentin diacetate;SPLENOPENTIN ACETATE SALT;ARG-LYS-GLU-VAL-TYR ACETATE;Splenopentin diacetate salt;SP-5, Splenin Fragment 32-36;Splenin pentapeptide (32-36);ARG-LYS-GLU-VAL-TYR ACETATE SALT;SPLENIN FRAGMENT 32-36 ACETATE SALT;Thymopoietin III pentapeptide (32-36)
CBNumber:
CB5384574
Molecular Formula:
C33H55N9O11
Molecular Weight:
753.84
MDL Number:
MFCD00133108
MOL File:
105184-37-0.mol
Last updated:2023-03-13 11:54:02

ARG-LYS-GLU-VAL-TYR ACETATE SALT Properties

storage temp. −20°C

SAFETY

Risk and Safety Statements

WGK Germany  3

ARG-LYS-GLU-VAL-TYR ACETATE SALT Chemical Properties,Uses,Production

Biological Activity

Splenopentin diacetate is a synthetic immunomodulatory pentapeptide corresponding to residues 32-36 of the spleen hormone spleen protein. It affects early T and B cell differentiation, thereby increasing the number of antibody-forming cells in gamma-irradiated mice.

in vitro

Splenopentin (1-100 μM) augments human NK cells and has no cytotoxicity.
Splenopentin (0.1 ng/mL-10 μg/mL; 3 h) induces phenotypic differentiation of both T- and B -cell precursor cells.

in vivo

Splenopentin (1 mg/kg; ip three times a week for 7-90 d) accelerates Langerhans cell recruitment and leads to pretreatment levels of Langerhans cell (LC) density in the skin of mice.
Splenopentin (0.01-100 μg per mouse; ip) has no demonstrable effect on neuromuscular transmission of mice.

Animal Model: Female Balb /c/Bln mice were injected Cyclophosphamide or Dexamethasone for 5 consecutive days
Dosage: 1 mg /kg
Administration: Ip three times a week for 7-90 days
Result: Reached the normal number of epidermal LCs at 28 days after the beginning of Cyclophosphamide treatment.
Accelerated restoration process and reached the normal LC density in the skin after 70 days in Dexamethasone treatment grops.

ARG-LYS-GLU-VAL-TYR ACETATE SALT Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 96)Suppliers
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Shanghai Daken Advanced Materials Co.,Ltd
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TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58

View Lastest Price from ARG-LYS-GLU-VAL-TYR ACETATE SALT manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ARG-LYS-GLU-VAL-TYR ACETATE SALT pictures 2022-10-12 ARG-LYS-GLU-VAL-TYR ACETATE SALT
105184-37-0
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
Splenopentin Acetate pictures 2021-07-13 Splenopentin Acetate
105184-37-0
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
Splenopentin Acetate pictures 2020-01-10 Splenopentin Acetate
105184-37-0
US $9.80 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
  • Splenopentin Acetate pictures
  • Splenopentin Acetate
    105184-37-0
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
ARG-LYS-GLU-VAL-TYR ACETATE SALT SPLENIN FRAGMENT 32-36 ACETATE SALT SPLENOPENTIN ACETATE SALT SP-5 ACETATE SALT ARG-LYS-GLU-VAL-TYR ACETATE SP-5, Splenin Fragment 32-36, Splenopentin L-Arginyl-L-lysyl-L-alpha-glutamyl-L-valyl-L-tyrosine diacetate Splenopentin diacetate ARG-LYS-GLU-VAL-TYR ACETATE SALT USP/EP/BP L-Tyrosine,N-[N-[N-(N2-L-arginyl-L-lysyl)-L-α-glutamyl]-L-valyl]-,diacetate (salt) SP-5, Splenin Fragment 32-36 4-[[6-amino-2-[[2-amino-5-(diaminomethylideneamino)-1-oxopentyl]amino]-1-oxohexyl]amino]-5-[[1-[[1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic a Splenin pentapeptide (32-36) Thymopoietin III pentapeptide (32-36) Splenopentin diacetate salt splenin,Inhibitor,Splenopentin diacetate,synthetic,immunomodulating,splenic,differentiation,inhibit,hormone,antibody,pentapeptide 105184-37-0 C31H51N9O9 C31H51N9O92C2H4O2 C33H55N9O11 Peptides Other Peptides BioChemical Amino Acids and Peptides Biochemicals and Reagents peptides pharm