9-(β-D-Xylofuranosyl)adenine
- CAS No.
- 524-69-6
- Chemical Name:
- 9-(β-D-Xylofuranosyl)adenine
- Synonyms
- Xa;Nsc7359;Nsc 7359;Xylosyl a;Xylosyladenine;Xylo-adenosine;Adenine xyloside;Xylo-adenosine, NSC7359;9-(-D-Xylofuranosyl)adenine;9-(b-D-Xylofuranosyl)adenine
- CBNumber:
- CB61456378
- Molecular Formula:
- C10H13N5O4
- Molecular Weight:
- 267.24
- MDL Number:
- MFCD30570252
- MOL File:
- 524-69-6.mol
| Melting point | 125-140 °C |
|---|---|
| Boiling point | 676.3±65.0 °C(Predicted) |
| Density | 2.08±0.1 g/cm3(Predicted) |
| pka | 13.11±0.70(Predicted) |
| InChI | InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13) |
| InChIKey | OIRDTQYFTABQOQ-UHFFFAOYSA-N |
| SMILES | O1C(CO)C(O)C(O)C1N1C2=C(N=C1)C(N)=NC=N2 |
9-(β-D-Xylofuranosyl)adenine Chemical Properties,Uses,Production
Uses
9-(β-d-Xylofuranosyl)adenine (xylo-A) was synthesized long ago and found to be effective in prolonging the survival time of mice bearing TA3 or Ehrlich ascites tumours. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. 9-(β-d-Arabinofuranosyl)adenine (vidarabine), which was reported to have similar antitumour properties to xylo-A, is now being used clinically as an antiviral agent[1].
Definition
ChEBI: A purine nucleoside in which adenine is attached to xylofuranose via a beta-N9-glycosidic bond.
References
[1] Yutaka Kubota. “Synthesis and antiviral evaluation of 4’-alkoxy analogues of 9-(beta-D-xylofuranosyl)adenine.” Antiviral Chemistry and Chemotherapy 19 5 (2009): 201–12.
9-(β-D-Xylofuranosyl)adenine Preparation Products And Raw materials
Raw materials
Preparation Products
9-(β-D-Xylofuranosyl)adenine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
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