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Diethyl fumarate

Diethyl fumarate structure

CAS No.: 623-91-6

Chemical Name:: Diethyl fumarate

Synonyms: ETHYL FUMARATE;Diethyl fuMara;iethylfumarate;Diethyl fuMarat;DIETHYL FUMARATE;Diethyl fumalate;Anti-Psoriaticum;diethyl furmarate;DiethylFumarate>RARECHEM AL BI 1505

CBNumber:: CB6220839

Molecular Formula:: C8H12O4

Molecular Weight:: 172.18

MDL Number:: MFCD00064455

MOL File:: 623-91-6.mol

Last updated:2024-04-03 17:07:09

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Diethyl fumarate Properties

Melting point	1-2 °C (lit.)
Boiling point	218-219 °C (lit.)
Density	1.052 g/mL at 25 °C (lit.)
refractive index	n20/D 1.44(lit.)
Flash point	197 °F
storage temp.	Sealed in dry,Room Temperature
solubility	3.1g/l
form	Liquid
color	Clear colorless to slightly yellow
Water Solubility	immiscible
BRN	775347
Dielectric constant	6.5（23℃）
Stability	Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases, reducing agents.
InChIKey	IEPRKVQEAMIZSS-AATRIKPKSA-N
LogP	2.200 (est)
CAS DataBase Reference	623-91-6(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances	ETHYL FUMARATE
EWG's Food Scores	1
FDA UNII	5WBU5A3E8A
NIST Chemistry Reference	2-Butenedioic acid (E)-, diethyl ester(623-91-6)
EPA Substance Registry System	Diethyl fumarate (623-91-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H227-H302

Precautionary statements

P210e-P264-P280a-P301+P312a-P403+P235-P501a

Hazard Codes

Risk Statements

Safety Statements

23-24/25

RIDADR

NA 1993 / PGIII

WGK Germany

RTECS

EM5950000

TSCA

Yes

HS Code

29171990

NFPA 704

	1
		0

Diethyl fumarate price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D95654	Diethyl fumarate 98%	623-91-6	5g	$107	2024-03-01	Buy
Sigma-Aldrich	D95654	Diethyl fumarate 98%	623-91-6	100g	$131	2024-03-01	Buy
TCI Chemical	F0068	Diethyl Fumarate >98.0%(GC)	623-91-6	25mL	$20	2024-03-01	Buy
TCI Chemical	F0068	Diethyl Fumarate >98.0%(GC)	623-91-6	500mL	$88	2024-03-01	Buy
Alfa Aesar	A16214	Diethyl fumarate, 98%	623-91-6	100g	$37.3	2023-06-20	Buy

Product number	Packaging	Price	Buy
D95654	5g	$107	Buy
D95654	100g	$131	Buy
F0068	25mL	$20	Buy
F0068	500mL	$88	Buy
A16214	100g	$37.3	Buy

Diethyl fumarate Chemical Properties,Uses,Production

Chemical Properties

colourless liquid

Uses

It is used as a pesticide or comonomer for the production of polystyrene.

Uses

Diethyl Fumarate is a reagent in the preparation of chiral hydroisoindolines via Diels-Alder cycloaddition which are potent, brain-penetrant, human neurokinin-1 receptor antagonists.

Uses

Diethyl fumarate is unsaturated polyester resins are used in applications, such as reinforced glass fiber for boats, piping, bathtubs, roof panels, etc., and as protective coatings, finishes, and lacquers.

Production Methods

Diethyl fumarate is manufactured via esterification of ethanol with fumaric acid.

Definition

ChEBI: A dieter obtained by the formal condensation of fumaric acid with ethanol.

Synthesis Reference(s)

The Journal of Organic Chemistry, 52, p. 323, 1987 DOI: 10.1021/jo00378a045
Tetrahedron Letters, 28, p. 6649, 1987 DOI: 10.1016/S0040-4039(00)96936-3

Purification Methods

Wash the fumarate with aqueous 5% Na2CO3, then with saturated CaCl2 solution, dry with CaCl2 and distil it. [Beilstein 2 IV 2207.]

Diethyl fumarate synthesis

Synthesis of Diethyl fumarate from Indoline and L(+)-Diethyl L-tartrate

Diethyl fumarate Preparation Products And Raw materials

Raw materials

Fumaric acid

Preparation Products

Monoethyl fumarate 2-BUTENE-1,4-DIOL Diethyl malate Ethyl ethoxyacetate ALPHA-CHLOROFUMARICACIDDIETHYLESTER

Diethyl fumarate Suppliers

Global( 331)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	16805	58
Hebei Saisier Technology Co., LTD	+86-18400010335 +86-13102810335	admin@hbsaisier.cn	China	892	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2141	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Shanghai Longyu Biotechnology Co., Ltd.	+8615821988213	info@longyupharma.com	China	2531	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Hebei Saisier Technology Co., LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
Shanghai Longyu Biotechnology Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from Diethyl fumarate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-12	Diethyl fumarate 623-91-6	US $6.00 / KG	1KG	More than 99%	2000KG/Month	Hebei Saisier Technology Co., LTD
2024-04-12	Diethyl fumarate 623-91-6	US $6.00 / KG	1KG	More than 99%	2000KG/Month	Hebei Saisier Technology Co., LTD
2024-01-22	Diethyl fumarate 623-91-6	US $8.00-0.80 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd

Diethyl fumarate
623-91-6
US $6.00 / KG
More than 99%
Hebei Saisier Technology Co., LTD

Diethyl fumarate
623-91-6
US $6.00 / KG
More than 99%
Hebei Saisier Technology Co., LTD

Diethyl fumarate
623-91-6
US $8.00-0.80 / KG
99%
Henan Fengda Chemical Co., Ltd

Diethyl fumarate Spectrum

Diethyl fumarate(623-91-6)MS Diethyl fumarate(623-91-6)¹HNMR Diethyl fumarate(623-91-6)¹³CNMR Diethyl fumarate(623-91-6)IR1 Diethyl fumarate(623-91-6)IR2 Diethyl fumarate(623-91-6)Raman

623-91-6(Diethyl fumarate )Related Search:

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Ferrous fumarate Tris(trimethylsilyl)phosphate Methyl acrylate Diethyl malonate DIETHYL PHOSPHATE

Ketotifen fumarate Quetiapine fumarate Monoethyl fumarate Monomethyl fumarate Diethyl ether

Dibutyl fumarate Diethyl oxalacetate sodium salt FUMARATE Ethyl Fumarate

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Diethyl fuMarat Diethyl (2E)-but-2-ene-1,4-dioate FuMaric acidethyl ester two Diethyl fuMara diethyl furmarate trans-2-butenedioicaciddiethylester DIETHYL TRANS-BUTENEDIOATE DIETHYL FUMARATE FUMARIC ACID DIETHYL ESTER ETHYL FUMARATE RARECHEM AL BI 1505 diethylfumarate (DEF) trans-2-Butenedioic acid diethyl ester~Fumaric acid diethyl ester Diethylfumarate,98% diethyl ester, (e)-2-butenedioic acid 2-Butenedioic acid (2E)-, diethyl ester Diethyl fumalate 1,4-Diethyl (2E)-but-2-enedioate 2-Butenedioic acid, diethyl ester, (E)- 2-Butenedioicacid(E)-,diethylester Anti-Psoriaticum Diethyl (2E)-2-butenedioate Diethyl ester of (E)-2-Butenedioic acid Diethylester kyseliny fumarove diethylester,(e)-2-butenedioicaci diethylesterkyselinyfumarove Diethyltrans-butenedicarboxylate Fumarsαurediαthylester (E)-2-Butenedioic acid diethyl ester TRANS-DIETHYL FUMARATE Diethyl trans-ethylene-1,2-dicarboxylate Fumaric acid diethyl Diethyl (E)-but-2-enedioate DIETHYL FUMARATE FOR SYNTHESIS DiethylFumarate> 2-Butenedioic acid (2E)-, 1,4-diethyl ester iethylfumarate Diethyl fumarate (ethyl fumarate) Fumars?ure-diethylester 2-Butenedioic acid(2E)-, 1,4-diethyl ester(623-91-6) Vanillin Impurity 13 623-91-6 C8H10O42 C8 to C9 Carbonyl Compounds Building Blocks Analytical Standards Alphabetic Analytical Chromatography Product Catalog Organic Building Blocks Esters DID - DIN Chemical Synthesis Organic Building Blocks Acids & Esters C8 to C9Alphabetic D DID - DIN