ChemicalBook >> CAS DataBase List >>N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide

CAS No.
330829-30-6
Chemical Name:
N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide
Synonyms
MRT-10;MRT-10 >=98% (HPLC);N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide;N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-3,4,5-trimethoxybenzamide;Benzamide, N-[[[3-(benzoylamino)phenyl]amino]thioxomethyl]-3,4,5-trimethoxy-;N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide;ShhN signaling,inhibit,MRT10,MRT 10,cancer,Smoothened,Smo,Smo-induced IP accumulation,MRT-10,Bodipy-cyclopamine,SAG-induced AP activity,Inhibitor
CBNumber:
CB62750479
Molecular Formula:
C24H23N3O5S
Molecular Weight:
465.52
MDL Number:
MFCD02734587
MOL File:
330829-30-6.mol
Last updated:2023-06-08 09:01:59

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Properties

storage temp. 2-8°C
solubility DMSO: ≥15mg/mL
form powder
color white to tan

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS09
Signal word  Danger
Hazard statements  H318-H410
Precautionary statements  P273-P280-P305+P351+P338-P501
Hazard Codes  Xi,N
Risk Statements  41-50
Safety Statements  26-39-61
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
NFPA 704
0
3 0

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22138 MRT10 ≥98% 330829-30-6 1mg $34 2024-03-01 Buy
Cayman Chemical 22138 MRT10 ≥98% 330829-30-6 5mg $100 2024-03-01 Buy
Cayman Chemical 22138 MRT10 ≥98% 330829-30-6 10mg $166 2024-03-01 Buy
Cayman Chemical 22138 MRT10 ≥98% 330829-30-6 25mg $371 2024-03-01 Buy
Tocris 4585 MRT10 ≥98% 330829-30-6 50 $680 2021-12-16 Buy
Product number Packaging Price Buy
22138 1mg $34 Buy
22138 5mg $100 Buy
22138 10mg $166 Buy
22138 25mg $371 Buy
4585 50 $680 Buy

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Chemical Properties,Uses,Production

Description

MRT10 is an antagonist of the Smoothened (Smo) receptor with an IC50 value of 0.64 μM in a luciferase reporter assay. It also inhibits bodipy-cyclopamine binding to the murine Smo receptor (IC50 = 0.5 μM) when expressed in HEK293 cells.

Uses

MRT 10, is a novel, high-affinity antagonist smoothened (Smo) receptor antagonist. It displaces labeled cyclopamine from Smo with an IC50 of 500 nM, and inhibits shh-induced Gli-reporter activity in Shh-light2 cells (IC50 = 0.64 μM).

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Suppliers

Global( 45)Suppliers
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TargetMol Chemicals Inc.
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Aladdin Scientific
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EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
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Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3500 55
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DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
MRT-10 N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-3,4,5-trimethoxybenzamide Benzamide, N-[[[3-(benzoylamino)phenyl]amino]thioxomethyl]-3,4,5-trimethoxy- MRT-10 >=98% (HPLC) N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide ShhN signaling,inhibit,MRT10,MRT 10,cancer,Smoothened,Smo,Smo-induced IP accumulation,MRT-10,Bodipy-cyclopamine,SAG-induced AP activity,Inhibitor 330829-30-6