trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
![trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Structure](CAS/20200331/GIF/3854-04-4.gif)
- CAS No.
- 3854-04-4
- Chemical Name:
- trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
- Synonyms
- CPD3509;Oxotremorine M (iodide);trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide
- CBNumber:
- CB63387012
- Molecular Formula:
- C11H19IN2O
- Molecular Weight:
- 322.19
- MDL Number:
- MFCD00055133
- MOL File:
- 3854-04-4.mol
- MSDS File:
- SDS
trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20847 | Oxotremorine M (iodide) ≥98% | 3854-04-4 | 50mg | $72 | 2024-03-01 | Buy |
| Cayman Chemical | 20847 | Oxotremorine M (iodide) ≥98% | 3854-04-4 | 100mg | $128 | 2024-03-01 | Buy |
| TRC | O870518 | Oxotremorine M | 3854-04-4 | 25mg | $140 | 2021-12-16 | Buy |
| AK Scientific | 1713CA | (4-(2-Oxo-1-pyrrolidinyl)-2-butynyl)trimethylammoniumiodide | 3854-04-4 | 50mg | $178 | 2021-12-16 | Buy |
| AK Scientific | 1713CA | (4-(2-Oxo-1-pyrrolidinyl)-2-butynyl)trimethylammoniumiodide | 3854-04-4 | 100mg | $240 | 2021-12-16 | Buy |
trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Chemical Properties,Uses,Production
Description
Oxotremorine M is a non-selective muscarinic (M) acetylcholine receptor agonist that induces phosphoinositide hydrolysis in mouse ileum isolated from wild-type, M2, M3, and M2/M3 knockout mice (EC50s = 0.36, 0.52, 1.62, and 1.48 μM, respectively). It also increases M4-induced inhibition of calcium currents in NG108-15 mouse neuroblastoma X rat glioma hybrid cells (EC50 = 0.14 μM). Oxotremorine M inhibits KCNQ2/3 potassium currents in Xenopus oocytes expressing M1 receptors and KCNQ2/3 potassium channels (IC50 = 1.1 μM). It also directly inhibits KCNQ2/3 potassium channels, decreasing KCNQ2/3 potassium currents in Xenopus oocytes lacking muscarinic receptors in a dose-dependent manner.
Uses
Oxotremorine M is a muscarinic receptor agonist.
storage
Desiccate at -20°C
trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Preparation Products And Raw materials
Raw materials
Preparation Products
trimethyl-[4-(2-oxopyrrolidin-1-yl)but-2-ynyl]azanium:iodide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 | sales-cpd@caerulumpharma.com | China | 3427 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| Zhengzhou Akem Chemical Co., Ltd | 13303867194 | 3001317055@qq.com | China | 9627 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 29778 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2380 | 58 |