Imazameth
- CAS No.
- 104098-48-8
- Chemical Name:
- Imazameth
- Synonyms
- CADRE;IMAZAPI;IMAZAPIC;IMAZAMETH;Imazapic 70%WG;AC 263, 222(TM);imazapic(bsi,iso);Imazapic, Pestanal;Pirarubicine Impurity 9;Imazapic@100 μg/mL in Acetonitrile
- CBNumber:
- CB6354097
- Molecular Formula:
- C14H17N3O3
- Molecular Weight:
- 275.3
- MDL Number:
- MFCD04307828
- MOL File:
- 104098-48-8.mol
| Melting point | 205-207°C |
|---|---|
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | 0-6°C |
| solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly, Sonicated) |
| pka | 10.72±0.40(Predicted) |
| color | White to Off-White |
| LogP | 2.470 |
| CAS DataBase Reference | 104098-48-8(CAS DataBase Reference) |
| FDA UNII | K98N09T10R |
| EPA Substance Registry System | Imazapic (104098-48-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H400-H410 |
| Precautionary statements | P273-P391-P501-P273-P391-P501 |
| WGK Germany | 3 |
| RTECS | US7079100 |
| HS Code | 29333990 |
Imazameth price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 34179 | Imazapic PESTANAL | 104098-48-8 | 100mg | $108 | 2024-03-01 | Buy |
| TRC | I268635 | Imazapic | 104098-48-8 | 500mg | $85 | 2021-12-16 | Buy |
| AK Scientific | J51132 | Imazapic | 104098-48-8 | 5g | $298 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0077251 | IMAZAPIC 95.00% | 104098-48-8 | 5G | $909.56 | 2021-12-16 | Buy |
| DC Chemicals | DC8678 | Imazapic >98% | 104098-48-8 | 1g | $300 | 2021-12-16 | Buy |
Imazameth Chemical Properties,Uses,Production
Uses
Imazapic can be used in analytical and biological studies of residue analysis and determination of imidazolinone herbicides in sunflower and soil by GC-MS.
Uses
Imazapic is registered throughout the world for use in peanuts, rangeland, sugarcane, and imidazolinoneresistant canola (12). A nonionic surfactant or oil adjuvant is required for maximum activity.
Definition
ChEBI: 5-methyl-2-[4-methyl-5-oxo-4-(propan-2-yl)-4,5-dihydro-1H-imidazol-2-yl]pyridine-3-carboxylic acid is a pyridinemonocarboxylic acid that is 5-methylpyridine-3-carboxylic acid which is substituted at position 2 by a 4,5-dihydro-imidazol-2-yl group, which in turn is substituted at positions 4, 4, and 5 by isopropyl, methyl, and oxo groups, respectively. It is a pyridinemonocarboxylic acid, an imidazolone, a member of imidazolines and a member of methylpyridines.
Pharmacology
Imazapic kills plants by inhibiting acetolactate synthase (ALS) (I50 = 1 μM), which is the first common enzyme in the biosynthesis of the branched chain amino acids, valine, leucine, and isoleucine. Imazapic is rapidly absorbed through the leaves of plants. Once it enters the plant, imazapic translocates to the growing points and growth ceases within 1 day after herbicide application followed by chlorosis and then necrosis of the growing points. Total plant death will occur within 2 to 3 weeks after treatment.
Environmental Fate
Imazapic is weakly to moderately adsorbed on sandy loam and silt loam soils. The Freundlich adsorption coefficient ranges from 0.17 to 2.99, (12). Because imazapic is a weak acid and exists in different ionic states, soil pH has an effect on soil binding properties. The anionic form predominates at soil pH as low as 5.5, and this form binds weakly to soil. The neutral or molecular form is important at soil pH from 4 to 6.5. This form binds to soil organic matter and clay. The cationic form is important at pH less than 4. Because the soil is a heterogeneous mixture of acid and base chemical groups, there may be sites within a particular soil that are 2 to 3 pH units higher or lower than the average pH. The cationic form will bind tightly to the lower pH components. Because of these interactions, small decreases in pH below 6 will result in large increases in binding. The half-life of imazapic in the soil is 106 d. Imazapic remains in the top 30 cm of the soil with low leaching potential. The degradation route of imazapic in the soil has not been determined.
Metabolism
Plant Metabolism. The selectivity of imazapic is due to
differential rates and routes of metabolism in tolerant
crops versus susceptible weeds(10). Imazapic
has excellent selectivity in peanuts, but is not selective in
soybeans. The difference in the tolerance of these two
legumes is due to the different routes of metabolism
of imazapic in the two crops. The primary metabolite
in soybeans is an imidazopyrrolo-pyridine derivative,
whereas in peanuts, the primary metabolite is the
glucose conjugate of hydroxy-imazapic. Although the
imidazopyrrolo-pyridine derivative formed in soybean is
immobile and is not an inhibitor of acetolactate synthase,
the rate of degradation of imazapic in soybeans is not rapid
enough for selectivity (10). In imidazolinone-resistant
crops, the primary mechanism of selectivity is due to
an altered acetolactate synthase that is not inhibited by
the imazapic (11).
Animal Metabolism (12). Metabolism studies in the rat
showed that imazapic is rapidly excreted in the urine.
There was no accumulation of imazapic or any of its
derivatives in the liver, kidney, muscle, fat, or blood.
Toxicity evaluation
Imazapic has shown no mutagenic or genotoxic activity in the Ames assay, mammalian cell gene mutation assay, in vitro chromosome aberration assay, in vitro unscheduled DNA synthesis (URS) assay, or the in vivo dominant lethal assay inmale rats. The acute toxicity and effects on wildlife and soil microflora of imazapic are shown in Table 6. This herbicide also has a low potential for bioaccumulation in fish.
Imazameth Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12468 | 58 |
| Hebei Kangcang new material Technology Co., LTD | +8615713292910 | Nancy@kangcang.com.cn | China | 341 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9341 | 55 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25363 | 58 |
View Lastest Price from Imazameth manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-11 | Imazapic
104098-48-8
|
US $20.00-10.00 / kg | 1kg | 98% | 20 | Hebei Kangcang new material Technology Co., LTD | |
 |
2023-10-16 | Imazameth
104098-48-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2023-09-06 | Imazameth
104098-48-8
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
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