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PF-1163B

CAS No.
258871-60-2
Chemical Name:
PF-1163B
Synonyms
PF-1163B;(-)-PF1163B;3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione;1-Oxa-4-azacyclotridecane-2,5-dione, 3-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10-dimethyl-13-pentyl-, (3S,10R,13R)-
CBNumber:
CB64666576
Molecular Formula:
C27H43NO5
Molecular Weight:
461.63
MDL Number:
MOL File:
258871-60-2.mol
Last updated:2023-05-21 10:59:17

PF-1163B Properties

Boiling point 649.9±50.0 °C(Predicted)
Density 1.027±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form An oil
pka 14.26±0.10(Predicted)

PF-1163B price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22066 PF-1163B ≥95% 258871-60-2 500μg $189 2024-03-01 Buy
Cayman Chemical 22066 PF-1163B ≥95% 258871-60-2 2.5mg $752 2024-03-01 Buy
AK Scientific 3563CC CID489140 258871-60-2 2.5mg $937 2021-12-16 Buy
Product number Packaging Price Buy
22066 500μg $189 Buy
22066 2.5mg $752 Buy
3563CC 2.5mg $937 Buy

PF-1163B Chemical Properties,Uses,Production

Description

PF-1163B is an antifungal agent produced by Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis (IC50 = 34 ng/ml). PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotoxic activity against mammalian cells.

Definition

ChEBI: PF 1163B is a macrolide antibiotic that is 4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione substituted by a 4-(2-hydroxyethoxy)benzyl group at position 3 and a pentyl group at position 13 (the 3S,10R,13S stereoisomer). It is isolated from Penicillium sp.PF1163 and exhibits antifungal activity against the pathogenic fungal strain Candida albicans TIMM1768. It has a role as an antifungal agent and a Penicillium metabolite. It is a macrolide antibiotic, a lactam and an aromatic ether.

PF-1163B Preparation Products And Raw materials

Raw materials

Preparation Products

PF-1163B Suppliers

Global( 9)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19743 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5141 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
PF-1163B (-)-PF1163B 1-Oxa-4-azacyclotridecane-2,5-dione, 3-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10-dimethyl-13-pentyl-, (3S,10R,13R)- 3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione 258871-60-2