1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl-
- CAS No.
- 2378619-75-9
- Chemical Name:
- 1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl-
- Synonyms
- 3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine;1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl-
- CBNumber:
- CB68237705
- Molecular Formula:
- C16H14N4S
- Molecular Weight:
- 294.37
- MDL Number:
- MOL File:
- 2378619-75-9.mol
1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 919950 | 3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine >98% | 2378619-75-9 | 100MG | $125 | 2024-03-01 | Buy |
Sigma-Aldrich | 919950 | 3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine >98% | 2378619-75-9 | 500MG | $370 | 2024-03-01 | Buy |
1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- Chemical Properties,Uses,Production
Uses
3-(([1,1′-Biphenyl]-4-ylmethyl)thio)-6-methyl-1,2,4,5-tetrazine (b-Tz) is a minimal tetrazine derivative capable of undergoing [4+2] Diels-Alder cycloaddition reactions with strained alkenes, which makes it highly useful in bioorthogonal labeling and cell detection applications. Tetrazines are often incorporated into chemical probes or other small-molecule tools using linkers that may impact physicochemical properties or the performance of the resulting conjugate product. Here, Lambert et al demonstrated the linker-free incorporation of b-Tz via silver-mediated Liebeskind-Srogl cross-coupling with a variety of aryl and heteroaryl boronic acids. This ″minimal″ tetrazine approach will facilitate the introduction of tetrazine into diverse complex molecules and improved probes for live-cell imaging and in vivo chemistry.
Supporting products
PdCl2(dppf): 697230
Ag2O: 226831
1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- Preparation Products And Raw materials
Raw materials
Preparation Products
1,2,4,5-Tetrazine, 3-[([1,1'-biphenyl]-4-ylmethyl)thio]-6-methyl- Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1360 | 58 |
Meryer (Shanghai) Chemical Technology Co., Ltd. | 18621169109 | market03@meryer.com | China | 27996 | 58 |
Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | market@aladdin-e.com | China | 48467 | 58 |