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AA-dUTP

CAS No.
85280-65-5
Chemical Name:
AA-dUTP
Synonyms
5-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (sodium salt)
CBNumber:
CB68397737
Molecular Formula:
C12H21N3NaO14P3
Molecular Weight:
547.22
MDL Number:
MOL File:
85280-65-5.mol
Last updated:2023-04-23 13:52:06

AA-dUTP Properties

solubility Water: Soluble

AA-dUTP Chemical Properties,Uses,Production

Description

5-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (aminoallyl-dUTP) is an amine-modified nucleotide that has been used in the synthesis of fluorescently labeled UTP.1 Incorporation of aminoallyl-dUTP into primers has been used in the generation of fluorescently labeled probes for DNA microarrays and FRET-based assays to measure the activity of reverse transcriptases.2,3

References

1. Kuznetsova, V.E., Spitsyn, M.A., Shershov, V.E., et al. Novel fluorescently labeled nucleotides: Synthesis, spectral properties and application in polymerase chain reaction Mendeleev Commun. 26(2),95-98(2016).
2. Xiang, C.C., Kozhich, O.A., Chen, M., et al. Amine-modified random primers to label probes for DNA microarrays Nat. Biotechnol. 20(7),738-742(2002).
3. Krebs, J.F., and Kore, A.R. Novel FRET-based assay to detect reverse transcriptase activity using modified dUTP analogues Bioconjug. Chem. 19(1),185-191(2008).

AA-dUTP Preparation Products And Raw materials

Raw materials

Preparation Products

AA-dUTP Suppliers

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5-(3-Aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (sodium salt) 85280-65-5