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2-Fluoroaniline

2-Fluoroaniline structure

CAS No.: 348-54-9

Chemical Name:: 2-Fluoroaniline

Synonyms: 2-fluroaniline;O-FLUOROANILINE;2-Fluorobenzenamine;AKOS 91139;2-Fluoranilin;FLUOROANILINE-2;2-FLUOROANILINE;AKOS BBS-00003628;1BO-Fluoroaniline;Aniline, o-fluoro-

CBNumber:: CB6853530

Molecular Formula:: C6H6FN

Molecular Weight:: 111.12

MDL Number:: MFCD00007642

MOL File:: 348-54-9.mol

MSDS File:: SDS

Last updated:2023-12-22 17:53:22

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2-Fluoroaniline Properties

Melting point	-29 °C
Boiling point	182-183 °C(lit.)
Density	1.151 g/mL at 25 °C(lit.)
vapor pressure	1 hPa (20 °C)
refractive index	n20/D 1.544(lit.)
Flash point	140 °F
storage temp.	Store below +30°C.
solubility	17g/l
pka	3.2(at 25℃)
form	Liquid
color	Clear colorless
Specific Gravity	1.151
Water Solubility	17 g/L (20°C)
BRN	1524219
CAS DataBase Reference	348-54-9(CAS DataBase Reference)
FDA UNII	SE32ZK6617
NIST Chemistry Reference	Benzenamine, 2-fluoro-(348-54-9)
EPA Substance Registry System	o-Fluoroaniline (348-54-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05,GHS07,GHS08,GHS09

Signal word

Danger

Hazard statements

H226-H302-H314-H373-H410

Precautionary statements

P210-P273-P280-P303+P361+P353-P305+P351+P338-P314

Hazard Codes

Xn,T,Xi

Risk Statements

22-37/38-41-36/38-33-23/24/25

Safety Statements

26-39-37/39-45-36/37-28

RIDADR

UN 2941 6.1/PG 3

WGK Germany

RTECS

BY1390000

Autoignition Temperature

600 °C

Hazard Note

Toxic/Irritant

TSCA

HazardClass

6.1

PackingGroup

III

HS Code

29214210

NFPA 704

	2
2		0

2-Fluoroaniline price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	F3401	2-Fluoroaniline ≥99%	348-54-9	25G	$33.2	2024-03-01	Buy
Sigma-Aldrich	F3401	2-Fluoroaniline ≥99%	348-54-9	500G	$344	2024-03-01	Buy
Sigma-Aldrich	8.20565	2-Fluoroaniline for synthesis	348-54-9	100mL	$178	2024-03-01	Buy
Sigma-Aldrich	F3401	2-Fluoroaniline ≥99%	348-54-9	100G	$83.4	2022-05-15	Buy
TCI Chemical	F0032	2-Fluoroaniline >99.0%(GC)	348-54-9	25g	$16	2024-03-01	Buy

Product number	Packaging	Price	Buy
F3401	25G	$33.2	Buy
F3401	500G	$344	Buy
8.20565	100mL	$178	Buy
F3401	100G	$83.4	Buy
F0032	25g	$16	Buy

2-Fluoroaniline Chemical Properties,Uses,Production

Chemical Properties

2-Fluoroaniline is a clear colorless to brown liquid, toxic, insoluble in water, soluble in ethanol and ether, its vapor and air can form an explosive mixture, which can cause combustion and explosion in case of fire and high heat. Reacts with oxidants. Decomposed by high heat to release toxic gases.

Uses

2-Fluoroaniline (cas# 348-54-9) is a useful reagent for the synthesis of insecticides.

Application

2-Fluoroaniline can be used to synthesize thermosensitive dye FH-102, which is a black thermosensitive dye with wide application and excellent performance. The dye can be used in the production of terminal output printing paper of electronic computer, EEG recording paper, telephone fax paper and transparent thermal film for oil field.

Definition

ChEBI: 2-fluoroaniline is a derivative of aniline in which the hydrogen at position 2 has been substituted by fluorine. It is used as a pharmaceutical intermediate It is a primary arylamine and a fluoroaniline.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 3415, 1984 DOI: 10.1016/S0040-4039(01)91034-2

General Description

Clear liquid with a mild sweet odor. Sinks in and mixes slowly with water.

Air & Water Reactions

Water soluble.

Reactivity Profile

2-Fluoroaniline is a base. Neutralizes acids to form salts plus water in an exothermic reaction. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

Inhalation or ingestion causes bluish tint to fingernails, lips and ears indicative of cyanosis; headache, drowsiness, and nausea, followed by unconsciousness. Liquid can be absorbed through skin and cause similar symptoms. Contact with eyes causes irritation.

Fire Hazard

Special Hazards of Combustion Products: Irritating and toxic hydrogen fluoride and oxides of nitrogen may form in fires.

Metabolic pathway

2-Fluoro and 3-fluoroanilines are preferentially hydroxylated at the para-position, and 4-fluoroaniline is both p- and o-hydroxylated to a significant extent by rat liver microsomes and is not accompanied with an NIH shift to give 4-hydroxyl-3-fluoroaniline.

2-Fluoroaniline Preparation Products And Raw materials

Raw materials

Ethyl 2-fluoropropionate 2-Nitrochlorobenzene Potassium fluoride Hydrogen 5-BROMO-2-FLUOROANILINE

4-Bromo-1-fluoro-2-nitrobenzene

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Preparation Products

Flufenoxuron carfentrazone-ethyl 4-Bromo-2-fluorobenzonitrile 2-FLUOROPHENYL ISOCYANATE 1-(2-FLUOROPHENYL)PIPERAZINE HYDROCHLORIDE

4-Chloro-2-fluoroaniline 3-Bromofluorobenzene N,N-Dimethyltryptamine (S)-3-AMINO-5-METHYL-2,3-DIHYDROBENZO[B][1,4]OXAZEPIN-4(5H)-ONE HCL 2-Fluoro-N-methylaniline

2-Bromo-3-fluoroaniline

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2-Fluoroaniline Suppliers

Global( 481)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	6000	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	16799	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Hi-Tech Chemistry Corp	0519-86626038	yuhh@hitechem.com	CHINA	811	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hi-Tech Chemistry Corp	58
Henan Tianfu Chemical Co.,Ltd.	55
Shanghai Time Chemicals CO., Ltd.	55
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58

View Lastest Price from 2-Fluoroaniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-10	2-Fluoroaniline 348-54-9	US $0.00 / KG	1KG	≥98%	300mt/year	Jinan Finer Chemical Co., Ltd
2023-12-23	2-Fluoroaniline 348-54-9	US $50.00-1.00 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-11-24	2-Fluoroaniline 348-54-9	US $30.00-10.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.

2-Fluoroaniline
348-54-9
US $0.00 / KG
≥98%
Jinan Finer Chemical Co., Ltd

2-Fluoroaniline
348-54-9
US $50.00-1.00 / KG
99%
Henan Fengda Chemical Co., Ltd

2-Fluoroaniline
348-54-9
US $30.00-10.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

2-Fluoroaniline Spectrum

2-Fluoroaniline(348-54-9)MS 2-Fluoroaniline(348-54-9)¹HNMR 2-Fluoroaniline(348-54-9)¹³CNMR 2-Fluoroaniline(348-54-9)IR1 2-Fluoroaniline(348-54-9)Raman 2-Fluoroaniline(348-54-9)ESR

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LABOTEST-BB LTBB000714 FLUOROANILINE-2 2-Fluoroaniline o-Fluoroaniline 2-FLUOROANILINE, 99+% 2-FluoroanilineForSynthesis 2-Fluoroaniline99.5% Aniline, 2-fluoro- Aniline, o-fluoro- 1,2-fluorobenzenamine 2-fluoro-benzenamin 2-fluoro-Benzenamine 2-Fluoro-phenylamine 2-Fluoroaniline, 97+% 2-FLUOROANILINE 2-Fluoranilin Benzenamine, 2-fluoro- 1-AMINO-2-FLUOROBENZENE AKOS 91139 AKOS BBS-00003628 Telmisartan Impurity 13 4-chlorobenzoic acid [8-[[4-[4-[[3-[(4-chlorophenyl)-oxomethoxy]-8-methyl-8-azoniabicyclo[3.2.1]octan-8-yl]methyl]phenyl]phenyl]methyl]-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl] ester dibromide 1BO-Fluoroaniline 2-Fluoroaniline> 2-Aminofluorobenzene 2-Fluoroaniline ISO 9001：2015 REACH 2-Fluoroaniline pure, 98% 2-fluroaniline 2-Fluorobenzenamine O-FLUOROANILINE Telmisartan Impurity U Abemaciclib Impurity 10 348-54-9 48-54-9 348-59-9 FC6H4NH2 C2 to C6 Building Blocks Amines Organic Building Blocks Nitrogen Compounds Fluoro-Aromatics Anilines, Aromatic Amines and Nitro Compounds Fluorobenzene Heterocyclic Compounds Benzene derivatives Fluorobenzene Series Fluorine series amine | alkyl Fluorine