ChemicalBook >> CAS DataBase List >>Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)-
Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)-
- CAS No.
- 1076225-26-7
- Chemical Name:
- Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)-
- Synonyms
- (rac)-PF-998425;Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)-
- CBNumber:
- CB69764031
- Molecular Formula:
- C14H14F3NO
- Molecular Weight:
- 269.26
- MDL Number:
- MOL File:
- 1076225-26-7.mol
Last updated:2023-08-31 17:58:56
Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)- Chemical Properties,Uses,Production
Biological Activity
(rac)-PF-998425 is a potent, selective, nonsteroidal androgen receptor (AR) antagonist. (rac)-PF-998425 has IC50 values of 26 and 90 nM in the AR binding and cellular assays, respectively. (rac)-PF-998425 has the potential for the research of the androgenetic alopecia[1].
References
[1]. Li JJ, et al. Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications. J Med Chem. 2008;51(21):7010-7014.
Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)- Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
| Jiangsu shring Biopharma Co., Ltd. | +8613372282299 | sales@shringchem.com | China | 3545 | 58 |
| Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 | market02@senwayer.com | China | 882 | 58 |
| Hebei Shengyuan Jinlong Import and Export Co. LTD | +8617367750398 | info@hebeisyjl.com | China | 1867 | 58 |
| Shaanxi Cuikang Pharmaceutical Technology Co., Ltd | +86-19164747840 +86-13119157289 | 13119157289@163.com | China | 2971 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29797 | 68 |
| Yichang Chanod Biomedical Technology Co,LTD | 0717-6855399 15377615856 | sales@sndswyy.cn | China | 84 | 58 |
| Hubei Zhaoke BIO-CHEMICAL Co., Ltd. | 027-87607080 13433334465 | 396587392@qq.com | China | 347 | 58 |
| Guangzhou Xinyanze Biotechnology Co., LTD | 18120340186 | 3239311947@qq.com | China | 375 | 58 |
View Lastest Price from Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)- manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-11-27 | (rac)-PF-998425
1076225-26-7
|
US $0.00 / gram | 1gram | 99% HPLC | 20 tons | Wuhan Senwayer Century Chemical Co.,Ltd | |
 |
2023-08-31 | PF-998425
1076225-26-7
|
US $0.00-0.00 / kg | 1kg | 99.9% | 20tons | Hebei Xinsheng New Material Technology Co., LTD. | |
 |
2023-08-21 | (rac)-PF-998425
1076225-26-7
|
US $30.00 / kg | 1kg | 99% | 1000t/year | Anhui Ruihan Technology Co., Ltd |
-
- (rac)-PF-998425
1076225-26-7
- US $0.00 / gram
- 99% HPLC
- Wuhan Senwayer Century Chemical Co.,Ltd
-
- PF-998425
1076225-26-7
- US $0.00-0.00 / kg
- 99.9%
- Hebei Xinsheng New Material Technology Co., LTD.
-
- (rac)-PF-998425
1076225-26-7
- US $30.00 / kg
- 99%
- Anhui Ruihan Technology Co., Ltd
Benzonitrile, 4-(2-hydroxycyclohexyl)-2-(trifluoromethyl)-
(rac)-PF-998425
1076225-26-7