CHYMOTRYPSINOGEN A
- CAS No.
- 9035-75-0
- Chemical Name:
- CHYMOTRYPSINOGEN A
- Synonyms
- EC 3.4.21.1;CHYMOTRYPSINOGEN;CHYMOTRYPSINOGEN A;α-ChyMotrypinogenA;Chymotrypsinogen B;α-Chymotrypsinogen A;Molecularweightmarker/CH;ALPHA-CHYMOTRYPSINOGEN A;Chymotrypsinogen (crystal;CHYMOTRYPSINOGEN A, BOVINE
- CBNumber:
- CB7167555
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MDL Number:
- MFCD00130483
- MOL File:
- Mol file
| storage temp. | -20°C |
|---|---|
| solubility | Soluble in 0.001M HCl. |
| form | essentially salt-free, lyophilized powder |
| FDA UNII | T97PCK86JR |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | 3 |
CHYMOTRYPSINOGEN A price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C4879 | α-Chymotrypsinogen A from bovine pancreas essentially salt-free, lyophilized powder | 9035-75-0 | 1g | $171 | 2024-03-01 | Buy |
| Sigma-Aldrich | C4879 | α-Chymotrypsinogen A from bovine pancreas essentially salt-free, lyophilized powder | 9035-75-0 | 5g | $597 | 2024-03-01 | Buy |
| Alfa Aesar | J64741 | Chymotrypsinogen A, from bovine pancreas | 9035-75-0 | 1g | $127 | 2023-06-20 | Buy |
| Alfa Aesar | J64741 | Chymotrypsinogen A, from bovine pancreas | 9035-75-0 | 5g | $419 | 2023-06-20 | Buy |
| Sigma-Aldrich | C4879 | α-Chymotrypsinogen A from bovine pancreas essentially salt-free, lyophilized powder | 9035-75-0 | 100mg | $62.6 | 2024-03-01 | Buy |
CHYMOTRYPSINOGEN A Chemical Properties,Uses,Production
Uses
α-Chymotrypsinogen A from bovine pancreas has been used as model protein crystallization reproducibility studies. It has also been used in the hydrolysis of α-gliadins prior to mass spectroscopy studies.
Uses
Chymotrypsinogen A is used as a serine protease that hydrolyzes peptide bonds with aromatic or large hydrophobic side chains (Tyr, Trp, Phe, Met) on the carboxyl end of the peptide bond, used in the non-invasive determination of solid-state protein conformation using near infrared (NIR) spectroscopy. It has been used to study the partitioning of protein in polymer/polymer aqueous two-phase systems. The enzyme has also been used for self-interaction chromatography applications, to test the rapid measurement of protein osmotic second virial coefficients. In this technique, the protein is immobilized on chromatographic particles and its retention is measured using isocratic elution.
General Description
Chymotrypsinogen from bovine pancreas is a zymogen containing 5 disulfide bridges. It has an isoelectric pH of 8.97.
Biochem/physiol Actions
Chymotrypsinogen A requires limited proteolysis for its activation. Chymotrypsinogen A may be activated by trypsin and chymotrypsin (autolytic activation) to form m α, β, γ, δ and π chymotrypsin (depending upon the conditions of activation). Chymotrypsin is a protease that will preferentially cleave peptides on the carboxyl side of aromatic amino acids including tryptophan, tyrosine, and phenylalanine. It will also hydrolyze peptides on the carboxyl side of leucine, methionine, and alanine.
CHYMOTRYPSINOGEN A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 | market03@meryer.com | China | 40240 | 62 |
| Adamas Reagent, Ltd. | 400-6009262 16621234537 | zhangsn@titansci.com | China | 14113 | 59 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9823 | 79 |