ChemicalBook >> CAS DataBase List >>[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester

[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester

CAS No.
866030-35-5
Chemical Name:
[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester
Synonyms
Aliskiren intermediate 1;InterMediate of Aliskiren;Tekturna(Aliskiren) intermediate;ALISKIREN INTERMEDIATE NO.866030-35-5;[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-...;[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-;(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methyl;(3S,5S)-5-[(1S,3S)-1-(Boc-amino)-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3-isopropyldihydrofuran-2(3H)-one;tert-Butyl ((1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-(4-Methoxy-3-(3-Methoxypropoxy)benzyl)-4-Methylpentyl)carbaMate;tert-butyl N-[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-5-oxo-4-propan-2-yloxolan-2-yl]pentyl]carbamate
CBNumber:
CB72510496
Molecular Formula:
C30H49NO7
Molecular Weight:
535.71
MDL Number:
MFCD20526612
MOL File:
866030-35-5.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester Properties

Boiling point 650.4±50.0 °C(Predicted)
Density 1.057
storage temp. 2-8°C
solubility Dichloromethane, Methanol
pka 11.81±0.46(Predicted)
FDA UNII S79DP4SNC5

[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M263256 [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamicAcid1,1-tert-ButylEster 866030-35-5 10mg $1410 2021-12-16 Buy
TRC M263256 [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamicAcid1,1-tert-ButylEster 866030-35-5 5mg $825 2021-12-16 Buy
AK Scientific 3584AC tert-Butyl((1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)carbamate 866030-35-5 250mg $1051 2021-12-16 Buy
Ark Pharm P000393437 tert-Butyl ((1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-(4-methoxy-3-(3-methoxypropoxy)benzyl)-4-methylpentyl)carbamate 95+% 866030-35-5 5g $1123 2021-12-16 Buy
American Custom Chemicals Corporation CCH0033542 TERT-BUTYL-((1S,3S)-1-((2S,4S)-4-ISOPROPYL-5-OXOTETRAHYDROFURAN-2-YL)-3-(4-METHOXY-3-(3-METHOXYPROPOXY)BENZYL)-4-METHYLPENTYL)CARBAMATE 95.00% 866030-35-5 1G $1575 2021-12-16 Buy
Product number Packaging Price Buy
M263256 10mg $1410 Buy
M263256 5mg $825 Buy
3584AC 250mg $1051 Buy
P000393437 5g $1123 Buy
CCH0033542 1G $1575 Buy

[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester Chemical Properties,Uses,Production

Uses

Intermediate in the preparation of Aliskiren.

173336-76-0
1236548-90-5
866030-35-5
Synthesis of [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester from 4-Bromo-1-methoxy-2-(3-methoxy-propoxy)-benzene and Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-
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[(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic acid tert-butyl ester CarbaMic acid, [(1S,3S)-3-[[4-Methoxy-3-(3-Methoxypropoxy)phenyl]Methyl]-4-Methyl-1-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]pentyl]-, 1,1-diMethylethyl ester (-)-Boc-Lactone: 5(S)-{l(S)-(tert-Butoxycarbonyl)aMino-3(S)-[4-Methoxy-3-(3-Methoxypropoxy)-benzyl]-4-Mthyl-pentyl}-3(S)-isopropyl-tetrahydrofuran-2-one N-[(1S,3S)-3-[[4-Methoxy-3-(3-Methoxypropoxy)phenyl]Methyl]-4-Methyl-1-[(2S, 4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]pentyl]carbaMic Acid 1,1-DiMethylethyl Ester InterMediate of Aliskiren [(1S,3S)-3-[[4-Methoxy-3-(3-Methoxypropoxy)phenyl]Methyl]-4-Methyl-1-[(2S,4S)-tetrahydro-4-(1-Methylethyl)-5-oxo-2-furanyl]pentyl]-, 1,1-diMethylethyl ester CarbaMic acid tert-Butyl ((1S,3S)-1-((2S,4S)-4-isopropyl-5-oxotetrahydrofuran-2-yl)-3-(4-Methoxy-3-(3-Methoxypropoxy)benzyl)-4-Methylpentyl)carbaMate tert-butyl N-[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-5-oxo-4-propan-2-yloxolan-2-yl]pentyl]carbamate Tekturna(Aliskiren) intermediate [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S, 4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]carbamic Acid 1,1-tert-Butyl Ester [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1- (1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methyl tert-butyl N-[(1S,3S)-1-[(2S,4S)-4-isopropyl-5-oxo-tetrahydrofuran-2-yl]-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-pentyl]carbamate Aliskiren intermediate 1 Carbamic acid, N-[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S,4S)-tetrahydro-4-(1-methylethyl)-5-oxo-2-furanyl]pentyl]-, 1,1-dimethylethyl ester ALISKIREN INTERMEDIATE NO.866030-35-5 [(1S,3S)-3-[[4-Methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-... (3S,5S)-5-[(1S,3S)-1-(Boc-amino)-3-[4-methoxy-3-(3-methoxypropoxy)benzyl]-4-methylpentyl]-3-isopropyldihydrofuran-2(3H)-one 866030-35-5 C30H49NO7 Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals