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4'-Methyl-2-cyanobiphenyl

CAS No.
114772-53-1
Chemical Name:
4'-Methyl-2-cyanobiphenyl
Synonyms
OTBN;2-Cyano-4'-methylbiphenyl;2MPPC;AKOS BAR-1203;Sartandiphenyl;Sartanbiphenyl;methyl diphenyl;-2-cyanobiphenyL;2-tolylbenzonitrile;2-hexylbenzonitrile
CBNumber:
CB7337004
Molecular Formula:
C14H11N
Molecular Weight:
193.24
MDL Number:
MFCD00151805
MOL File:
114772-53-1.mol
MSDS File:
SDS
Last updated:2024-04-08 17:36:13

4'-Methyl-2-cyanobiphenyl Properties

Melting point 49 °C
Boiling point >320°C
Density 1,17 g/cm3
vapor pressure 0.014Pa at 20℃
Flash point >320°C
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Crystalline Powder
color Off-white to beige
BRN 3605954
LogP 3.5 at 23℃
CAS DataBase Reference 114772-53-1(CAS DataBase Reference)
FDA UNII O417TI15TA
NIST Chemistry Reference Benzonitrile, 2-(4-methylphenyl)-(114772-53-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08,GHS09
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H302-H312-H332-H313-H361-H372-H401-H411
Precautionary statements  P280-P201-P260-P301+P312a-P405-P501a-P261-P264-P270-P271-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38-48/25/62/51/53-22
Safety Statements  22-26-36/37/39-36/37/45/57-20-36
WGK Germany  3
Hazard Note  Irritant
HS Code  27075000
NFPA 704
1
2 0

4'-Methyl-2-cyanobiphenyl price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C1446 2-Cyano-4'-methylbiphenyl >99.0%(GC) 114772-53-1 10g $37 2024-03-01 Buy
Alfa Aesar B21273 2-Cyano-4'-methylbiphenyl, 98+% 114772-53-1 5g $50.8 2024-03-01 Buy
Alfa Aesar B21273 2-Cyano-4'-methylbiphenyl, 98+% 114772-53-1 25g $162 2024-03-01 Buy
Alfa Aesar B21273 2-Cyano-4'-methylbiphenyl, 98+% 114772-53-1 100g $431 2024-03-01 Buy
TRC M294115 4''-Methylbiphenyl-2-carbonitrile 114772-53-1 25g $185 2021-12-16 Buy
Product number Packaging Price Buy
C1446 10g $37 Buy
B21273 5g $50.8 Buy
B21273 25g $162 Buy
B21273 100g $431 Buy
M294115 25g $185 Buy

4'-Methyl-2-cyanobiphenyl Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

4'-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α.

Synthesis

4'-Methyl-2-cyanobiphenyl is prepared by the reaction of o-cyanobromobenzene and potassium (4-methylphenyl)trifluoroborate. The specific synthesis steps are as follows:
General procedure: A mixture of aryl halide (0.5 mmol), potassium aryltrifluoroborate (0.6 mmol), K2CO3 (1.0 mmol), Pd/C (5%; 0.5 mol%), ethanol (3 mL), and distilled water (1 mL) was stirred at 80 °C in air for the time indicated. The reaction mixture was added to brine (15 mL) and extracted with ethyl acetate (4×15 mL). The organic solvent was removed under vacuum, and the product was isolated by short-column chromatography.
4'-Methyl-2-cyanobiphenyl synthesis

Global( 636)Suppliers
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Henan Fengda Chemical Co., Ltd
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18871490254 linda@hubeijusheng.com CHINA 28180 58

View Lastest Price from 4'-Methyl-2-cyanobiphenyl manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4'-Methyl-2-cyanobiphenyl pictures 2024-04-17 4'-Methyl-2-cyanobiphenyl
114772-53-1
US $0.00 / KG 1KG 99% 200mt Jinan Finer Chemical Co., Ltd
4′-methyl-2-cyanobiphenyl pictures 2024-04-08 4′-methyl-2-cyanobiphenyl
114772-53-1
US $0.00-0.00 / Kg 1Kg 99.9% 200tons airuikechemical co., ltd.
4'-Methyl-2-cyanobiphenyl pictures 2023-12-26 4'-Methyl-2-cyanobiphenyl
114772-53-1
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd

4'-Methyl-2-cyanobiphenyl Spectrum

2-cyanogen radical-4'-methyl biphenyl 2-[(4-methyl)pentyl]-benzonitrile 4'-Methyl-2-Cyano Diphenyl AKOS BAR-1203 4'-METHYLBIPHENYL-2-CARBONITRILE 4'-METHYL-2-BIPHENYLCARBONITRILE 4'-METHYL-2-CYANOBIPHENYL 4'-METHYL[1,1'-BIPHENYL]-2-CARBONITRILE 2-(4-TOLYL)-BENZONITRILE 2-(4-METHYLPHENYL)BENZONITRILE [2-(P-TOLYL)BENZONITRILE] 2-cyano-4methylbiphenyl 4'-Methylbiphenyl-2-carbonitrile 2-CYANO-4''-METHYLBIPHENYL (OTBN) 4''-METHYL-2-CYANO-BIPHENYL (FOR LOSARTAN) 2-CYANO-4''-METHYLBIPHENYL(SARTANBIPHENYL) 2-tolylbenzonitrile 2-CYANO-4''-METHYLBIPHENYL 99%MIN Sartandiphenyl 4-Cyanomethylbiphenyl OTBN (O-Tolybenzenitrile) Sartanbiphenyl o-(p-Tolyl)benzonitrile 4'-Methyl-2-cyanobiphenyl,98% 2-(4-Methylphenyl)benzenecarbonitrile 2MPPC 4'-Methyl-2-cyanobipheny 4'-Methyl-2-cyanobip 4'-Methyl-2-cyanobiphenyl ( OTBN ) diethyl 3-(3-acetyl-6-nitro-9H-carbazol-9-yl)propylphosphonate [1,1'-Biphenyl]-2-carbonitrile, 4'-Methyl- 4'-Methyl-2-cyanobiphenyl SynonyMs 4'-Methylbiphenyl-2-carbonitrile methyl diphenyl 2-hexylbenzonitrile Telmisartan Impurity 15 2-Cyano-4'-methylbiphenyl > 2-methyl-2-cyanobiphenyl -2-cyanobiphenyL OTBN 4’-Methyl-2-Cyano-Biphenyl 4'-Methyl-2-cyanobiphenyl ISO 9001:2015 REACH OTBN 2-Cyano-4'-methylbiphenyl Ortho Tolyl Benzonitrile (OTBN) 4'-methyl-[1,1'-biphenyl]-2-carbonitrile 4'-Methyl-2-cyanobiphenyl 114772-53-1 114772-53-21 114772-83-1 14772-53-1 CH3C6H4C6H4CN Biphenyl & Diphenyl ether (intermediate of telmisartan) (intermediate of sartan) (intermediate of sartan s product) Losartan Potassium Biphenyl derivatives INTERMEDIATESOF Starting Raw Materials & Intermediates cyanide