ChemicalBook >> CAS DataBase List >>Cycloleucine
Cycloleucine
- CAS No.
- 52-52-8
- Chemical Name:
- Cycloleucine
- Synonyms
- x201;X 201;CYCLEU;cb1639;wr14997;CB 1639;nsc1026;wr14,997;WR 14997;H-CLE-OH
- CBNumber:
- CB7376009
- Molecular Formula:
- C6H11NO2
- Molecular Weight:
- 129.16
- MDL Number:
- MFCD00001381
- MOL File:
- 52-52-8.mol
- MSDS File:
- SDS
Last updated:2024-03-26 17:16:27
| Melting point | 320 °C (dec.) (lit.) |
|---|---|
| Boiling point | 239.22°C (rough estimate) |
| Density | 1.1426 (rough estimate) |
| refractive index | 1.4827 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO: < 1 mg/mL (ultrasonic) (insoluble or slightly soluble) |
| form | Crystalline Flakes or Powder |
| pka | 2.38±0.20(Predicted) |
| color | White to beige |
| Water Solubility | 5 g/100 mL |
| Merck | 14,2734 |
| BRN | 636626 |
| CAS DataBase Reference | 52-52-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 0TQU7668EI |
| NCI Drug Dictionary | cycloleucine |
| NIST Chemistry Reference | Cyclopentanecarboxylic acid, 1-amino-(52-52-8) |
| EPA Substance Registry System | Cyclopentanecarboxylic acid, 1-amino- (52-52-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P301+P310+P330 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GY2625000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29224999 | |||||||||
| Toxicity | LD50 oral in rat: 290mg/kg | |||||||||
| NFPA 704 |
|
Cycloleucine price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A48105 | Cycloleucine 97% | 52-52-8 | 10g | $190.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | A48105 | Cycloleucine 97% | 52-52-8 | 5g | $203 | 2024-03-01 | Buy |
| TCI Chemical | A1063 | 1-Aminocyclopentanecarboxylic Acid >98.0%(T) | 52-52-8 | 1g | $36 | 2024-03-01 | Buy |
| TCI Chemical | A1063 | 1-Aminocyclopentanecarboxylic Acid >98.0%(T) | 52-52-8 | 5g | $102 | 2024-03-01 | Buy |
| Alfa Aesar | B22179 | 1-Aminocyclopentanecarboxylic acid, 97+% | 52-52-8 | 1g | $30.65 | 2024-03-01 | Buy |
Cycloleucine Chemical Properties,Uses,Production
Chemical Properties
WHITE TO BEIGE CRYSTALLINE FLAKES OR POWDER
Uses
Cycloleucine can be used as a building block to synthesize:
- Phosphonylmethylaminocyclopentane-1-carboxylic acid by reacting with paraformaldehyde and diethylphosphite via Kabachnik-Field′s reaction.
- Benzo[b]thiophene-2-carboxylic acid {1-[1-(R)-(3-morpholin-4-ylpropylcarbamoyl)-2-phenylethylcarbamoyl]cyclopentyl}-amide, (MEN14268) as potential tachykinin NK2 receptor antagonist.
Uses
NMDA receptor antagonist, inhibits nucleic acid methylation; adrenergic agonist
Uses
Cycloleucine is a synthetic amino acid used in numerous biochemical transport studies
Definition
ChEBI: A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
General Description
Cycloleucine is a nonmetabolizable amino acid widely used as a building block in peptide synthesis.
Purification Methods
Any Cl -or other anions are removed by stirring with a strong cation exchange resin (Amberlite IR-120), filtering, and washing with distilled H2O until the filtrate is free from the anion. The resin is then stirred overnight with 6N NH4OH, filtered, the filtrate is decolourised (charcoal) and evaporated to dryness in a vacuum. The residue is recrystallised from H2O/EtOH. Also crystallise it from aqueous EtOH. The hydrochloride has m 222-224o(dec). [Neelakantan & Hartung J Org Chem 23 967 1958, Connors & Ross J Chem Soc 2119 1960. O’Donnell et al. Synthesis 127 1984, Beilstein 14 IV 974.]
Cycloleucine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 304)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 16805 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
View Lastest Price from Cycloleucine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-26 | Cycloleucine
52-52-8
|
US $30.00-0.80 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2022-10-19 | Cycloleucine
52-52-8
|
US $100.00 / kg | 1kg | 99% | 100 tons | Hebei Duling International Trade Co. LTD | |
 |
2021-07-13 | Cycloleucine
52-52-8
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- Cycloleucine
52-52-8
- US $30.00-0.80 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Cycloleucine
52-52-8
- US $100.00 / kg
- 99%
- Hebei Duling International Trade Co. LTD
-
- Cycloleucine
52-52-8
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
52-52-8(Cycloleucine)Related Search:
6-Aminocaproic acid
Acetaminophen
Cyclopentanecarboxylic acid
Tris(hydroxymethyl)aminomethane
Cyclopentyl chloride
1of4
WR 14997
wr14,997
wr14997
X 201
x201
H-AC5C-OH
H-CLE-OH
H-NH(1)CPEN-OH
CYCLOLEUCINE
CYCLEU
1-AMINOCYCLOPENTANE-1-CARBOXYLIC ACID
1-AMINOCYCLOPENTANECARBOXYLIC ACID
1-AMINO-1-CYCLOPENTANECARBOXYLIC ACID
1-AMINO-1-CARBOXYCYCLOPENTANE
Cycloleucine≥ 98% (HPLC)
RARECHEM AK HD C019
TIMTEC-BB SBB004230
1-amino-cyclopentanecarboxylicaci
Amino-1-cyclopentanecarboxylic acid
CB 1639
cb1639
Cycloleucin
Cyclopentanecarboxylic Acid, 1-amino-, L-
Cyclopentanecarboxylic acid, L-amino
1-Aminocyclopentanecarboxylate
Cyclopentanecarboxylic acid, 1-amino-
1-AMINO-1-CYCLOPENTANECARBOXYLIC ACID, 9 7%
1-Aminocyclopentane-3,3,4,4-D4-1-carboxylic Acid
Cycloleucine-carboxyl-13C, 2,2,5-D3
1-Aminocyclo-pentanecarboxylic acid Cycloleucine
1-AMINOCYCLOPENTANCARBOXYLICACID
Cycloleucine carboxylic acid
1-Amino-1-cyclopentanecarboxylicacid(Cycloleucine)
1-Carboxycyclopentylamine
1-Aminocyclopentanecarboxylic acid, 97+%
H-Cycloleu-OH
Cycloleucine,1-Aminocyclopentanecarboxylic acid
1-Amino-1-cyclopenta
Cyclolencine
NSC 112194
NSC 112195
NSC 112197
1-AMino-1-cyclopentanecarboxylic acid, 97% 5GR
l-cyclopentanecarboxylicaci
NSC 1026
nsc1026
WR 14,997
Irbint-A02
1-Aminocyclopentanecarboxylic Acid >
Cycloleucine USP/EP/BP
Irbesartan Impurity 18
Irbesartan Impurity 37
TIANFU-CHEM - Cycloleucine
Ionotropic glutamate receptors,inhibit,glycine,NMDA,cytostatic,nucleic,Inhibitor,Cycloleucine,methylations,anxiolytic,transferase,iGluR,ATP
52-52-8
1G/瓶[52-52-8
1G/瓶52-52-8
H2NC5H8CO2H