ChemicalBook >> CAS DataBase List >>Acetovanillone
Acetovanillone
- CAS No.
- 498-02-2
- Chemical Name:
- Acetovanillone
- Synonyms
- APOCYNIN;4-HYDROXY-3-METHOXYACETOPHENONE;1-(4-HYDROXY-3-METHOXYPHENYL)ETHAN-1-ONE;Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-;Acetovanilone;ACETOVANILLON;Apocynin (Acetovanillone);4'-HYDROXY-3'-METHOXYACETOPHENONE;Apocynin - CAS 498-02-2 - Calbiochem;NSC 2146
- CBNumber:
- CB7484931
- Molecular Formula:
- C9H10O3
- Molecular Weight:
- 166.17
- MDL Number:
- MFCD00008747
- MOL File:
- 498-02-2.mol
- MSDS File:
- SDS
Last updated:2024-04-19 20:05:26
| Melting point | 112-115 °C (lit.) |
|---|---|
| Boiling point | 263-265 °C/17 mmHg (lit.) |
| Density | 1.1708 (rough estimate) |
| refractive index | 1.5101 (estimate) |
| Flash point | >230 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly), Methan |
| pka | 8.18±0.18(Predicted) |
| form | Solid |
| color | Yellow to brown |
| Odor | at 100.00 %. faint sweet vanillin |
| Odor Type | vanilla |
| Water Solubility | soluble in hot water |
| Merck | 14,741 |
| BRN | 637373 |
| LogP | 1.389 (est) |
| CAS DataBase Reference | 498-02-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | B6J7B9UDTR |
| NIST Chemistry Reference | Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-(498-02-2) |
| EPA Substance Registry System | Acetovanillone (498-02-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | AM8800000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29145000 | |||||||||
| NFPA 704 |
|
Acetovanillone price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | A10809 | 4′-Hydroxy-3′-methoxyacetophenone 98% | 498-02-2 | 25g | $41.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | 178385 | Apocynin - CAS 498-02-2 - Calbiochem A cell-permeable, anti-inflammatory phenolic compound that acts as a potent and selective inhibitor of NADPH oxidase. | 498-02-2 | 1g | $96.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | 73536 | Acetovanillone analytical standard | 498-02-2 | 100mg | $62.8 | 2022-05-15 | Buy |
| TCI Chemical | H0261 | 4'-Hydroxy-3'-methoxyacetophenone >98.0%(GC) | 498-02-2 | 25g | $69 | 2024-03-01 | Buy |
| TCI Chemical | H0261 | 4'-Hydroxy-3'-methoxyacetophenone >98.0%(GC) | 498-02-2 | 100g | $207 | 2024-03-01 | Buy |
Acetovanillone Chemical Properties,Uses,Production
Chemical Properties
yellowish to brown powder
Uses
Acetovanillone is an inhibitor of NADPH oxidase (an enzyme responsible for reactive oxygen species production) and is useful in the treatment of various inflammatory diseases.
Uses
4'-Hydroxy-3'-methoxyacetophenone is used as an inhibitor of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, which is an enzyme responsible for reactive oxygen species production. It is also useful in the treatment of various inflammatory diseases and atherosclerosis. Further, it shows an anti-inflammatory activity and improves endothelial function by reducing oxidative stress. In addition to this, it is used for studying nitric oxide regulated processes in plants.
Preparation
Also obtained by Fries rearrangement of guaiacol acetate in the presence of zinc chloride.
Definition
ChEBI: An aromatic ketone that is 1-phenylethanone substituted by a hydroxy group at position 4 and a methoxy group at position 3.
Synthesis Reference(s)
The Journal of Organic Chemistry, 60, p. 739, 1995 DOI: 10.1021/jo00108a046
General Description
Acetovanillone is an aromatic plant ketone, which is a selective inhibitor of NADPH oxidase. It is mainly secreted in the urine of mammals as the corresponding glucuronide conjugate.
storage
Store at RT
Purification Methods
Crystallise apocynin from water, or EtOH/pet ether. [Beilstein 8 IV 1814.]
Acetovanillone Preparation Products And Raw materials
Raw materials
Preparation Products
Acetylacetone
4-Hydroxy-3-methoxystyrene
METHOXYBENZOQUINONE
4-chloro-6,7-dimethoxyquinoline
1-(2-hydroxy-3-methoxy-phenyl)ethanone
1of3
Global( 509)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12467 | 58 |
| Hubei Langyou International Trading Co., Ltd | +8618874586545 | linda@xrdchem.cn | China | 197 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 16801 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 1034 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from Acetovanillone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-20 | 3-Methoxy-4-hydroxyacetophenone
498-02-2
|
US $600.00 / Kg | 1Kg | 98 | 500 Kg | R&D Scientific Inc. | |
 |
2024-04-05 | Acetovanillone
498-02-2
|
US $8.00-3.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2024-03-26 | Acetovanillone
498-02-2
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd |
-
- 3-Methoxy-4-hydroxyacetophenone
498-02-2
- US $600.00 / Kg
- 98
- R&D Scientific Inc.
-
- Acetovanillone
498-02-2
- US $8.00-3.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Acetovanillone
498-02-2
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
498-02-2(Acetovanillone)Related Search:
2'-Methoxyacetophenone
2'-Hydroxyacetophenone
4'-Bromoacetophenone
2',4'-Dichloroacetophenone
3'-Methylacetophenone
3-Nitroacetophenone
4-Nitroacetophenone
3',5'-Dimethoxyacetophenone
3-Methoxyacetophenone
CHLOROPHOSPHONAZO III
1of4
1-(4-hydroxy-3-methoxyphenyl)-ethanon
1-(4-Hydroxy-3-methoxyphenyl)-ethanone (acetovanillone)
1-(4-HYDROXY-3-METHOXYPHENYL) ETHANONE
Acetovanillone~Apocynin
4'-Hydroxy-3'-Methoxyacetophenone 3-Methoxy-4-Hydroxyacetophenone 3'-Methoxy-4'-Hydroxyacetophenone
ACETOVANILLONE 98+%
acetovanillone,1-(4-hydroxy-3-methoxyphenyl)-ethanone,apocynin
ACETAVANILLONE
Ethanone,1-(4-hydroxy-3-me
ETHANONE,1-(4-HYDROXY-3-METHO
Acetovanillone, 98% 100GR
ACETOVANILLONE (4-HYDROXY-3-METHOXYACETOPHENONE)
4'-hydroxy-3'-methoxyacetophenone,1-(4-hydroxy-3-methoxy)ethanone
4-Acetylguaiacol
Acetovanillone ,99%
4μ-Hydroxy-3μ-methoxyacetophenone, Acetovanillone, Apocynin
1-(4-Hydroxy-3-methoxyphenyl)ethan-1-one, Acetovanillone
4’-hydroxy-3’-methoxy-acetophenon
4-Acetyl-2-methoxyphenol
4-Hydroxy-3-methoxyphenyl methyl ketone
Acetoguaiacon
Acetoguaiacone
Acetophenone, 4'-hydroxy-3'-methoxy-
Acetovanyllon
-Acetylguaiacol
Apocynine
-Hydroxy-3-methoxyphenyl methyl keton
-Methoxy-4-acetylphenol
'-Methoxy-4'-hydroxyacetophenone
Phenol, 4-acetyl-2-methoxy
3-Metoksy-4-hydroksyacetofenon
TIMTEC-BB SBB008060
AURORA KA-3667
ACETOVANILLONE
AKOS BBS-00003229
3'-METHOXY-4'-HYDROXYACETOPHENONE
3-METHOXY-4-HYDROXYACETOPHENONE
NSC 209524
NSC 2146
Acetovanillon/ Apocynin
2-Methoxy-4-acetylphenol
Acetoguaicone
Apocynin, >=98%
AcetovaniL
Vanilloyl methyl keton
Acetovanillone, 98.5%
4-Hydroxy 3-Methoxy Acetophenone (Acetovanillone)
Acetovanillone, 98.5%, for synthesis
4'-Hydroxy-3'-methoxyacetophenone>
Aetovanillone
cetovanillone
4-Hydroxy -3-Methoxy Acetophennoe (Acetovanillone)
Food Grade Acetovanillone Powder CAS 498-02-2 with Best Price
1-(4-HYDROXY-3-METHOXYPHENYL)ETHAN-1-ONE
Ethanone, 1-(4-hydroxy-3-methoxyphenyl)-
Acetovanilone
APOCYNIN
ACETOVANILLON