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3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester

CAS No.
7163-25-9
Chemical Name:
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester
Synonyms
3-Hydroxy-2-naphthoic acid ethyl ester;Ethyl 3-hydroxynaphthalene-2-carboxylate;3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester;3-Hydroxy-naphthalene-2-carboxylic acid ethyl ester;2-Naphthalenecarboxylic acid, 3-hydroxy-, ethyl ester
CBNumber:
CB82263942
Molecular Formula:
C13H12O3
Molecular Weight:
216.23
MDL Number:
MFCD00220608
MOL File:
7163-25-9.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Properties

Melting point 79.0 to 83.0 °C
Boiling point 291°C(lit.)
Density 1.1652 (rough estimate)
refractive index 1.5090 (estimate)
solubility soluble in Toluene
form powder to crystal
pka 9.53±0.40(Predicted)
color White to Orange to Green

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
HS Code  2918290090
NFPA 704
1
2 0

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical E1249 Ethyl 3-Hydroxy-2-naphthoate >98.0%(GC) 7163-25-9 1g $57 2024-03-01 Buy
TCI Chemical E1249 Ethyl 3-Hydroxy-2-naphthoate >98.0%(GC) 7163-25-9 5g $284 2024-03-01 Buy
TRC E940608 Ethyl 3-Hydroxy-2-naphthoate 7163-25-9 50mg $155 2021-12-16 Buy
Apolloscientific OR27972 Ethyl 3-Hydroxy-2-naphthoate 7163-25-9 1g $206 2021-12-16 Buy
SynQuest Laboratories 2629-1-Z9 Ethyl 3-hydroxy-2-naphthoate 7163-25-9 1g $228 2021-12-16 Buy
Product number Packaging Price Buy
E1249 1g $57 Buy
E1249 5g $284 Buy
E940608 50mg $155 Buy
OR27972 1g $206 Buy
2629-1-Z9 1g $228 Buy

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Chemical Properties,Uses,Production

Uses

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis

Synthesis_7163-25-9
To a round bottom flask were added 5 g 3-hydroxy-2-naphthalic acidand 16 mL ethanol. The reaction mixture was refluxed for 6 h. After thecompletion of the reaction, the reaction mixture was cooled down to room temperature and washed with distilled water. The organic layerwas recovered and washed with saturated sodium bicarbonate followedby drying with anhydrous MgSO4. The MgSO4 was removed by filtrationand the filtrate was dried under reduced pressure. The resulted solid waspurified by silica chromatography with petroleum ether and ethyl acetate(10:1, v/v) as eluent to give the compound ethyl 3-hydroxy-2-naphthoate(4.1229 g, yield 70.60%).

92-70-6
7163-25-9
Synthesis of 3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester from 3-Hydroxy-2-naphthoic acid

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2169 58
Jinan Liheng Biotechnology Co., Ltd.
15865262812 info@lihengpharm.com CHINA 938 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Cochemical Co. Ltd.
+86-029-86115547 +86-17791676824 sales@cochemical.com China 3953 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24539 81
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10269 58
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28398 80
3-Hydroxy-2-naphthalenecarboxylic acid ethyl ester 3-Hydroxy-2-naphthoic acid ethyl ester Ethyl 3-hydroxynaphthalene-2-carboxylate 2-Naphthalenecarboxylic acid, 3-hydroxy-, ethyl ester 3-Hydroxy-naphthalene-2-carboxylic acid ethyl ester 7163-25-9