2-(Hydroxymethyl)isonicotinic acid
- CAS No.
- 915140-06-6
- Chemical Name:
- 2-(Hydroxymethyl)isonicotinic acid
- Synonyms
- 2-Hydroxymethylisonicotinic acid;2-(hydroxymethyl)-4-pyridinecarboxylic acid;4-PYRIDINECARBOXYLIC ACID, 2-(HYDROXYMETHYL)-
- CBNumber:
- CB82468677
- Molecular Formula:
- C7H7NO3
- Molecular Weight:
- 153.14
- MDL Number:
- MFCD11977439
- MOL File:
- 915140-06-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
2-(Hydroxymethyl)isonicotinic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0388281 | 2-(HYDROXYMETHYL)ISONICOTINIC ACID 95.00% | 915140-06-6 | 5MG | $497.45 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 35932 | 2-(Hydroxymethyl)isonicotinicacid 95+% | 915140-06-6 | 1g | $880 | 2021-12-16 | Buy |
| Chemenu | CM178301 | 2-(Hydroxymethyl)isonicotinicacid 95% | 915140-06-6 | 5g | $1122 | 2021-12-16 | Buy |
| Chemenu | CM178301 | 2-(Hydroxymethyl)isonicotinicacid 95% | 915140-06-6 | 10g | $1683 | 2021-12-16 | Buy |
| Chemenu | CM178301 | 2-(Hydroxymethyl)isonicotinicacid 95% | 915140-06-6 | 25g | $2992 | 2021-12-16 | Buy |
2-(Hydroxymethyl)isonicotinic acid Chemical Properties,Uses,Production
Synthesis
Ethyl 2-(hydroxymethyl)isonicotinate (iso-EhmnH) (4.84 g, 26.7 mmol) was dissolved in THF/H2O (40 mL, v:v = 1:1). KOH (4.58 g, 81.6 mmol, 3 eq.) was added as solid and the mixture stirred at 100 °C for 20 h and then cooled to r.t. The mixture was further cooled in ice-water and then HNO3 added to adjust the pH to 4–5. The solvent was removed under vacuum. The organic part in the solid mixture was then extracted twice with 400 mL of ethanol and the solvent removed. The powder contains inorganic material was added in hot isopropanol and then filtered, evaporation of iso-propanol yielded iso-hmnH2 as white powder. Yield 2.93 g, 72%[1].
References
[1] Armaghan M, et al. Isolation of first row transition metal–carboxylate zwitterions. RSC Advances, 2015; 5: 42978-42989.
2-(Hydroxymethyl)isonicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-(Hydroxymethyl)isonicotinic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
| Shanghai Gubang New Materail Technology Co. LTD | 21-51317962 +8618721305404 | 16728589@qq.com | CHINA | 272 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3144 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +86-512-68323967 +86-18015559028 | sales1@artkmedchem.com | China | 39009 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 4056 | 55 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66099280 17798518460 | cfzhang@aikonchem.com | China | 19918 | 55 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
| Shanghai Brain Biotechnology Co., Ltd. | 13564638271 | sales@brain-biot.com | China | 2961 | 55 |