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ChemicalBook >> CAS DataBase List >>(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Structure
(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one structure
CAS No.
347323-96-0
Chemical Name:
(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one
Synonyms
ITX 3;CS-1227;ITX3,ITX-3;ITX3 >=98% (HPLC);Trio N-Terminal RhoGEF Domain Inhibitor, ITX3;Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 - CAS 347323-96-0 - Calbiochem;2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-thiazolo[3,2-a]benzimidazol-3(2H)-one;Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-;2-((2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one;(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one
CBNumber:
CB82518888
Molecular Formula:
C22H17N3OS
Molecular Weight:
371.45
MDL Number:
MFCD02629172
MOL File:
347323-96-0.mol
MSDS File:
SDS
Last updated:2023-09-04 15:51:00
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(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Properties

Boiling point 589.5±60.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Store at +4°C
solubility DMSO: ≥4mg/mL
form Yellow solid
pka 0.17±0.20(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I1411 ITX3 ≥98% (HPLC) 347323-96-0 5mg $108 2024-03-01 Buy
Sigma-Aldrich 645890 Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 347323-96-0 10mg $159 2024-03-01 Buy
Sigma-Aldrich I1411 ITX3 ≥98% (HPLC) 347323-96-0 25mg $322 2024-03-01 Buy
Tocris 3792 ITX3 ≥99%(HPLC) 347323-96-0 10 $177 2021-12-16 Buy
Tocris 3792 ITX3 ≥99%(HPLC) 347323-96-0 50 $745 2021-12-16 Buy
Product number Packaging Price Buy
I1411 5mg $108 Buy
645890 10mg $159 Buy
I1411 25mg $322 Buy
3792 10 $177 Buy
3792 50 $745 Buy

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Chemical Properties,Uses,Production

Uses

ITX3 is a nontoxic inhibitor of TrioN, the N-terminal GEF domain of the multidomain Trio protein. ITX 3 specifically inhibited endogenous TrioN activity.

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Suppliers

Global( 40)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
SPIRO PHARMA eric_feng1954@126.com China 9254 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3500 55
Musechem +1-800-259-7612 info@musechem.com United States 4662 60
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012 sales@regentsciences.com China 9294 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Haoyuan Chemexpress Co., Ltd. 61
SPIRO PHARMA 55
EMMX Biotechnology LLC 60
BOC Sciences 65
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Musechem 60
Shenzhen Regent Biochemical Technology Co., Ltd. 58

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one Spectrum

(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one(347323-96-0)1HNMR
(E)-2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]thiazolo[3,2-a]benzimidazol-3(2H)-one ITX 3 2-[(2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]-thiazolo[3,2-a]benzimidazol-3(2H)-one Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 CS-1227 Trio N-Terminal RhoGEF Domain Inhibitor, ITX3 - CAS 347323-96-0 - Calbiochem Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-[(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene]- ITX3 >=98% (HPLC) ITX3,ITX-3 2-((2,5-Dimethyl-1-phenyl-1H-pyrrol-3-yl)methylene)benzo[4,5]imidazo[2,1-b]thiazol-3(2H)-one 347323-96-0