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ChemicalBook >> CAS DataBase List >>2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Structure
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate structure
CAS No.
1041026-71-4
Chemical Name:
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate
Synonyms
tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate;tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1);2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate;6-diazaspiro[3.3]heptane-2-carboxylate oxalate;1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97%;1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97%;2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1);2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate;ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate;tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate
CBNumber:
CB82548539
Molecular Formula:
C22H38N4O8
Molecular Weight:
486.56
MDL Number:
MFCD12404932
MOL File:
1041026-71-4.mol
Last updated:2023-04-23 13:52:06
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2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Properties

Melting point 206-209℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Slightly, Sonicated)
form Solid
color White to Off-White
Water Solubility Slightly soluble in water.
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312
Precautionary statements  P264-P270-P280h-P301+P312a-P321-P501a
HS Code  2933399990
NFPA 704
1
2 0

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Alfa Aesar H63763 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97% 1041026-71-4 250mg $163 2023-06-20 Buy
Alfa Aesar H63763 1-Boc-2,6-diazaspiro[3.3]heptane hemioxalate, 97% 1041026-71-4 1g $519 2023-06-20 Buy
TRC D417620 2,6-Diazaspiro[3.3]heptane-2-carboxylicAcidtert-ButylEsterHemioxalate 1041026-71-4 100mg $70 2021-12-16 Buy
Synthonix D6051 2,6-Diazaspiro[3.3]heptane-2-carboxylicacidtert-butylesterhemioxalate 97.0% 1041026-71-4 1g $30 2021-12-16 Buy
Apolloscientific OR312002 2,6-Diazaspiro[3.3]heptane,N2-BOCprotectedhemioxalate 97% 1041026-71-4 1g $58 2021-12-16 Buy
Product number Packaging Price Buy
H63763 250mg $163 Buy
H63763 1g $519 Buy
D417620 100mg $70 Buy
D6051 1g $30 Buy
OR312002 1g $58 Buy

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Chemical Properties,Uses,Production

Chemical Properties

white to yellow Solid.

Uses

2,6-Diazaspiro[3.3]heptane-2-carboxylic Acid tert-Butyl Ester Hemioxylate is preparation of pyrimidine derivatives and related heterocycles as CDK inhibitors for treatment of diseases.

Uses

It is employed as a intermediate for pharmaceutical.

Preparation

Synthesis of 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate: Take a 500mL single-necked bottle, add 6-toluenesulfonyl-2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester (7g, 20mmol), dissolve in methanol (200mL), add magnesium chips (3.84 g) g, 0.16 mol, 8 equiv) and stirred at room temperature. The reaction solution gradually turned into a white viscous state with the dissolution of the magnesium scraps, and TLC showed that the reaction of the raw materials was completed. The solvent was removed by rotary evaporation, ether (150 mL) was added, stirred at room temperature for 1 h, filtered through celite, the filtrate was dried over anhydrous sodium sulfate, and an ethanol solution (3 mL) of anhydrous oxalic acid (0.89 g, 9.9 mmol, 0.5 equiv) was added dropwise, A white precipitate appeared immediately, which was filtered under reduced pressure to give 3.2 g of a colorless solid, 82%.

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Preparation Products And Raw materials

Raw materials

Preparation Products

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Suppliers

Global( 156)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Victorypharm Co.,Ltd.
+86-13916956214 sales@victory-pharm.com China 1301 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Hi-Tech Chemistry Corp 		0519-86626038 yuhh@hitechem.com CHINA 811 58
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9341 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
Supplier Advantage
Suzhou Victorypharm Co.,Ltd.
58
Capot Chemical Co.,Ltd. 		60
Hi-Tech Chemistry Corp 		58
Hangzhou FandaChem Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Accela ChemBio Inc. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58

View Lastest Price from 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-(tert-butoxycarbonyl)-6-aza-2-azoniaspiro[3.3]heptane oxalate pictures 2022-09-08 6-(tert-butoxycarbonyl)-6-aza-2-azoniaspiro[3.3]heptane oxalate
1041026-71-4
 US $0.00-0.00 / KG 1KG 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate pictures 2021-10-22 tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
1041026-71-4
 US $0.00 / KG 1KG 97%min 10KG WUHAN FORTUNA CHEMICAL CO., LTD
tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate pictures 2019-07-06 tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate
1041026-71-4
 US $1.00 / KG 1KG 95% 500KG Career Henan Chemical Co

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate Spectrum

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate(1041026-71-4)1HNMR2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate(1041026-71-4)FT-IR

1041026-71-4(2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxylate)Related Search:

tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate hydrochloride tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate 2,3,3a,8a-Tetrahydro-1H-2-aza-cyclopenta[a]inden-8-one 1-Oxa-4,8-diazaspiro[5.5]undecan-8-carboxylic acid tert-butyl ester
3-Azabicyclo[3.1.0]hexane-3,6-dicarboxylic acid 3-tert-butyl ester 7-Boc-1,7-diaza-spiro[4.4]nonane Tert-butyl 2,6-diazaspiro[3.4]octane-6-carboxylate 1-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRROLE 2-(3-(TERT-BUTOXYCARBONYL)-3-AZASPIRO[5.5]UNDECAN-9-YL)ACETIC ACID
Carbamic acid, 3-azabicyclo[3.1.0]hex-1-yl-, 1,1-dimethylethyl ester (9CI) 4-OXO-HEXAHYDRO-CYCLOPENTA[C]PYRROLE-2-CARBOXYLIC ACID TERT-BUTYL ESTER TERT-BUTYL 1-OXO-2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLATE BICYCLO[2.2.2]OCTANE-1,4-DICARBOXYLIC ACID HEMIMETHYL ESTER Tert-butyl 1,7-diazaspiro[4,4]nonane-1-carboxylate
Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate benzyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 2S-7-Aza-bicyclo[2.2.1]heptane-2,7-dicarboxylic acid 7-tert-butyl ester

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2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester heMioxylate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, ethanedioate (2:1) 1-Boc-2,6-diazaspiro[3.3]heptane heMioxalate, 97% tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate, hemioxalate salt 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 1,1-diMethylethyl ester, heMioxalate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid 1,1-dimethylethyl ester ethanedioate tert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate 2,6-diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester oxalate 2,6-diaza-spiro[3.3]heptane-2-carboxylic acid tert-butyl ester, oxalic acid salt 2-Boc-2,6-diazaspiro[3.3]heptane Hemioxalate 2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester hemioxalate 2,6-Diazaspiro[3.3]heptane, N2-BOC protected hemioxalate 2,6-Diazaspiro[3.3]heptane-2-carboxylic acid ethanedioate, 1,1-dimethylethyl ester 2-Methyl-2-propanyl 2,6-diazaspiro[3.3]heptane-2-carboxylate ethanedioate (2:1) 1-Boc-2,6-diazaspiro[3.3]heptanehemioxalate,97% 2,6-diazo-heterospiro [3,3] heptane-2-carboxylic acid tert-butyl semicarbamate 6-diazaspiro[3.3]heptane-2-carboxylate oxalate tert-butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate oxalate(2:1) 3-Oxazolidinecarboxylicacid,2,2-dimethyl-4-(2-oxoethyl)-,1,1-dimethylethylester,(10S)- 2-Boc-2,6-Diazaspiro[3.3]heptane ethanedioate (2:1) ert-Butyl 2,6-diazaspiro[3,3]heptane-2-carboxylate hemioxalate tert-Butyl 2,6-diazaspiro[3.3]heptane-2-carboxylate semioxalate 1041026-71-4 2C10H18N2O2C2H2O4