CUDA
- CAS No.
- 479413-68-8
- Chemical Name:
- CUDA
- Synonyms
- CUDA;CUDA Exclusive;HPTJABJPZMULFH-UHFFFAOYSA-N;Dodecanoic acid, 12-[[(cyclohexylamino)carbonyl]amino]-;PPARalpha,epoxide,Peroxisome proliferator-activated receptors,cardiovascular,Inhibitor,peroxisome,Soluble,inhibit,disease,receptor,sEH,proliferator-activated,PPAR,Epoxide Hydrolase,hypotensive,CUDA,PPARα,hydrolase,lipid-lowering
- CBNumber:
- CB82590750
- Molecular Formula:
- C19H36N2O3
- Molecular Weight:
- 340.5
- MDL Number:
- MFCD12912266
- MOL File:
- 479413-68-8.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
CUDA price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10007923 | CUDA ≥98% | 479413-68-8 | 5mg | $47 | 2024-03-01 | Buy |
| Cayman Chemical | 10007923 | CUDA ≥98% | 479413-68-8 | 10mg | $87 | 2024-03-01 | Buy |
| Cayman Chemical | 10007923 | CUDA ≥98% | 479413-68-8 | 25mg | $206 | 2024-03-01 | Buy |
| Cayman Chemical | 10007923 | CUDA ≥98% | 479413-68-8 | 50mg | $360 | 2024-03-01 | Buy |
| ChemScene | CS-0082718 | CUDA ≥98.0% | 479413-68-8 | 5mg | $365 | 2021-12-16 | Buy |
CUDA Chemical Properties,Uses,Production
Definition
ChEBI: 12-[(Cyclohexylcarbamoyl)amino]dodecanoic acid is a medium-chain fatty acid.
Biological Activity
cuda is a soluble epoxide hydrolase (seh) inhibitor.epoxyeicosatrienoic acid metabolites of arachidonic acid, such as 11(12)-eet and 14(15)-eet, have been identified as endothelium derived hyperpolarizing factors with vasodilator activity. soluble epoxide hydrolase (seh) can catalyze the conversion of eets to the corresponding dihydroxy eicosatrienoic acids thereby diminishing their activity.
in vitro
in a previous study, in order to test if the cuda’s mechanism of action is retained upon structural modification, the dissociation constants of cuda was evaluated for mouse seh. results showed that for cuda, competitive a tight-binding inhibition kinetic was obtained with r2 > 0.99. moreover, the ki value of 3.8 nm was obtained for cuda. in addition, it was found that cuda was an inhibitor of seh exhibiting ic50 values of 11.1 nm and 112 nm for the mouse and human enzymes, respectively [1].
IC 50
11.1 and 112 nm for the mouse and human soluble epoxide hydrolase, respectively
References
[1] c. morisseau, m. h. goodrow, j. w. newman, et al. structural refinement of inhibitors of urea-based soluble epoxide hydrolases. biochemical pharmacology 63, 1599-1608 (2002).
CUDA Preparation Products And Raw materials
Raw materials
Preparation Products
CUDA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3501 | 55 |
| Xibao Biotechnology (Shanghai) Co., Ltd. | 13761246140 | 58642714@qq.com | China | 415 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-020-82000279 18988968278 | sales@ubiochem.com | China | 2434 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |