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Sacubitril Impurity 7

CAS No.
149709-44-4
Chemical Name:
Sacubitril Impurity 7
Synonyms
LBQ657;LCZ696-4;Sacubitrilat;Deethyl Sakuba;LCZ-696 Impurity 1;SACUBITRIL DI ACID;Diacid of Sacubitril;LCZ696 impurities124;LBQ-657(Sacubitrilat);Sacubitrilat (LBQ-657)
CBNumber:
CB83133439
Molecular Formula:
C22H25NO5
Molecular Weight:
383.44
MDL Number:
MFCD00921225
MOL File:
149709-44-4.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:11

Sacubitril Impurity 7 Properties

Boiling point 705.4±60.0 °C(Predicted)
Density 1?+-.0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM)
form A crystalline solid
pka 4.59±0.23(Predicted)
FDA UNII SPI5PBF81S

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338

Sacubitril Impurity 7 price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19829 LBQ657 ≥98% 149709-44-4 1mg $33 2024-03-01 Buy
Cayman Chemical 19829 LBQ657 ≥98% 149709-44-4 5mg $131 2024-03-01 Buy
Cayman Chemical 19829 LBQ657 ≥98% 149709-44-4 10mg $245 2024-03-01 Buy
Cayman Chemical 19829 LBQ657 ≥98% 149709-44-4 25mg $894 2021-12-16 Buy
TRC D288245 DesethylSacubitril 149709-44-4 10mg $580 2021-12-16 Buy
Product number Packaging Price Buy
19829 1mg $33 Buy
19829 5mg $131 Buy
19829 10mg $245 Buy
19829 25mg $894 Buy
D288245 10mg $580 Buy

Sacubitril Impurity 7 Chemical Properties,Uses,Production

Uses

Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.

Sacubitril Impurity 7 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 105)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
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BOC Sciences
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Career Henan Chemica Co
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LEAP CHEM CO., LTD.
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Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33350 58
LBQ657 Sacubitrilat (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid LCZ696-4 Diacid of Sacubitril LCZ-696 Impurity 1 Sacubitrilat (LBQ-657) Sacubitril Desethyl Impurity LCZ696 Impurity 900-04 Deethyl Sakuba Sacubitril metabolite LBQ 657 [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)- 4-[[(1S,3R)-1-[([1,1'-Biphenyl]-4-yl)methyl]-3-methyl-4-hydroxy-4-oxobutyl]amino]-4-oxobutanoic acid (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)- 2-methylpentanoic aci Diacid of Sacubitril/ Sacubitril Desethyl Impurity/ Sacubitrilat LCZ696 impurities124 Sacubitril metabolite LBQ 657Q: What is Sacubitril metabolite LBQ 657 Q: What is the CAS Number of Sacubitril metabolite LBQ 657 Q: What is the storage condition of Sacubitril metabolite LBQ 657 Q: What are the applications of Sacubitril metabolite LBQ 657 quinoline,6-bromo-7-chloro- SACUBITRIL DI ACID Salcubatra calcium impurity J LBQ-657(Sacubitrilat) LCZ696 impurity 900-04(LBQ657) Sacubitril Diacid Impurity (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid 149709-44-4 14709-44-4