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PD168393
- CAS No.
- 194423-15-9
- Chemical Name:
- PD168393
- Synonyms
- CS-2316;PD 168393;PD168393 USP/EP/BP;PD-168393;PD 168393;PD168393;PD-168393;PD 168393;4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide;N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
- CBNumber:
- CB8316129
- Molecular Formula:
- C17H13BrN4O
- Molecular Weight:
- 369.22
- MDL Number:
- MFCD02179207
- MOL File:
- Mol file
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
| Melting point | 279℃ |
|---|---|
| Boiling point | 571.1±50.0 °C(Predicted) |
| Density | 1.558±0.06 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO |
| form | powder |
| pka | 12.19±0.43(Predicted) |
| color | white to beige |
| FDA UNII | 3R996Y9T0I |
PD168393 price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 513033 | PD 168393 - CAS 194423-15-9 - Calbiochem | 194423-15-9 | 1mg | $201 | 2024-03-01 | Buy |
| Sigma-Aldrich | PZ0285 | PD168393 ≥98% (HPLC) | 194423-15-9 | 5MG | $115 | 2023-06-20 | Buy |
| Sigma-Aldrich | PZ0285 | PD168393 ≥98% (HPLC) | 194423-15-9 | 25MG | $451 | 2023-06-20 | Buy |
| Cayman Chemical | 21059 | PD 168393 ≥95% | 194423-15-9 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 21059 | PD 168393 ≥95% | 194423-15-9 | 5mg | $100 | 2024-03-01 | Buy |
PD168393 Chemical Properties,Uses,Production
Uses
PD 168393, is an irreversible epidermal growth factor receptor (EGFR) inhibitor.
Uses
PD168393 has been used in the acute inhibition of ErbB4.
Definition
ChEBI: A member of the class of quinazolines carrying bromoanilino and acrylamido substituents at positions 4 and 6 respectively.
Biochem/physiol Actions
PD168393 is a 6-acrylamido-4-anilinoquinazoline compound. It increases apoptosis in malignant peripheral nerve sheath tumor cells, stimulated by lysosomal dysfunction.
target
EGFR
PD168393 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 129)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
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| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 27690 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
194423-15-9(PD168393)Related Search:
4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE
PD 168393
N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide
2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide
PD168393;PD-168393;PD 168393
CS-2316
N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
PD-168393;PD 168393
PD168393 USP/EP/BP
194423-15-9
Inhibitors