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Boc-5-aminopentanoic acid

CAS No.
27219-07-4
Chemical Name:
Boc-5-aminopentanoic acid
Synonyms
BOC-5-AVA-OH;BOC-5-AMINOVALERIC ACID;5-(TERT-BUTOXYCARBONYLAMINO)VALERIC ACID;BOC-APE(5)-OH;Boc-5-Ava-OH 97%;BOC-NH-(CH2)4-COOH;RARECHEM EM WB 0073;Boc-d-aMinovaleric acid;5-(BOC-AMINO)VALERIC ACID;N-BOC-5-AMINOVALERIC ACID
CBNumber:
CB8379946
Molecular Formula:
C10H19NO4
Molecular Weight:
217.26
MDL Number:
MFCD00076903
MOL File:
27219-07-4.mol
MSDS File:
SDS
Last updated:2023-09-20 16:43:00

Boc-5-aminopentanoic acid Properties

Melting point 48-52 °C(lit.)
Boiling point 160-168 °C0.8 mm Hg(lit.)
Density 1.1518 (rough estimate)
refractive index 1.4500 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
form Powder
pka 4.72±0.10(Predicted)
color Off-white
BRN 2048862
CAS DataBase Reference 27219-07-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
10-21
HazardClass  IRRITANT
HS Code  29241990
NFPA 704
1
2 0

Boc-5-aminopentanoic acid price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 475351 Boc-5-Ava-OH 97% 27219-07-4 5g $166 2023-06-20 Buy
Sigma-Aldrich 475351 Boc-5-Ava-OH 97% 27219-07-4 25g $658 2023-06-20 Buy
TCI Chemical B2895 N-(tert-Butoxycarbonyl)-5-aminovaleric Acid >98.0%(GC)(T) 27219-07-4 5g $89 2024-03-01 Buy
TCI Chemical B2895 N-(tert-Butoxycarbonyl)-5-aminovaleric Acid >98.0%(GC)(T) 27219-07-4 25g $301 2024-03-01 Buy
Alfa Aesar H66168 5-(Boc-amino)valeric acid, 95% 27219-07-4 1g $26.7 2023-06-20 Buy
Product number Packaging Price Buy
475351 5g $166 Buy
475351 25g $658 Buy
B2895 5g $89 Buy
B2895 25g $301 Buy
H66168 1g $26.7 Buy

Boc-5-aminopentanoic acid Chemical Properties,Uses,Production

Description

Boc-5-aminopentanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Boc-5-aminopentanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

solid

Uses

Boc-5-aminovaleric acid can be used to synthesize inhibitors of bacterial quorum seining and biofilm formation. It can also be used to synthesize diblock and triblock copolymers.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 2424, 1983 DOI: 10.1021/jo00162a028

24424-99-5
660-88-8
27219-07-4
Synthesis of Boc-5-aminopentanoic acid from Di-tert-butyl dicarbonate and 5-AMINOVALERIC ACID
Global( 172)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
GenicBio Limited
+86-21-37621270 service@genicbio.com CHINA 991 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2169 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58

View Lastest Price from Boc-5-aminopentanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Boc-5-aminopentanoic acid pictures 2020-01-08 Boc-5-aminopentanoic acid
27219-07-4
US $3.00 / KG 1KG 98% 200KG Career Henan Chemical Co
N-T-BUTOXYCARBONYL-5-AMINOPENTANOIC ACID N-DELTA-T-BUTOXYCARBONYL-DELTA-AMINOVALERIC ACID N-BOC-5-AMINOPENTANOIC ACID N-BOC-5-AMINOVALERIC ACID PENTANOIC ACID, 5-[[(1,1-DIMETHYLETHOXY)CARBONYL]AMINO]- RARECHEM EM WB 0073 5-(TERT-BUTOXYCARBONYLAMINO)PENTANOIC ACID 5-(BOC-AMINO)PENTANOIC ACID 5-(BOC-AMINO)VALERIC ACID 5-[(tert-Butyloxycarbonyl)amino]pentanoic acid 5-[[(1,1-Dimethylethyl)oxy]carbonyl]aminopentanoic acid BOC-NH-(CH2)4-COOH BOC-APE(5)-OH BOC-5-AMINOPENTANOIC ACID BOC-DELTA-AMINOVALERIC ACID Boc-5-AMinovaleric acid Boc-5-AMinovaleric acid 5-(Boc-amino)pentanoic acid, 5-(Boc-amino)valeric acid 5-(tert-Butoxycarbonylamino)pentanoic Acid N-Boc-5-aminovaleric Acid N-Boc-5-aminopentanoic Acid Boc-d-aMinovaleric acid N-(tert-Butoxycarbonyl)-5-aMinovaleric Acid Boc-5-Ava-OH 97% Boc-2-amino-5-phenylpentanoic acid DCHA N-(tert-Butoxycarbonyl)-5-aminovaleric Acid Boc-5-aminovaleric acid≥ 97% (HPLC) 5-(Boc-amino)valeric AcidN-Boc-5-aminovaleric Acid N-(tert-Butoxycarbonyl)-5-aminop (Tert-Butoxy)Carbonyl 5-Ava-OH N-(tert-Butoxycarbonyl)-5-aminovaleric Acid > 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid 5-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoicaci N-(tert-Butoxycarbonyl)-5-aminopentanoic Acid Boc-5-aminopentanoic acid USP/EP/BP tert-butyl 1-phenyl-2,9,12,15-tetraoxaheptadecan-17-oate 5-(TERT-BUTOXYCARBONYLAMINO)VALERIC ACID BOC-5-AMINOVALERIC ACID BOC-5-AVA-OH 5-[[(1,1-Dimethylethoxy)carbonyl]amino]pentanoic acid PROTAC Linkers,Inhibitor,protac,Boc NH C4 acid,inhibit,BocNHC4acid,Boc-NH-C-4-acid,linker 5-(N-BOC-Amino)pentanoic acid 27219-07-4 CH33CO2CNHCH24CO2H CARBOXYLIC ACID Unnatural Amino Acid Derivatives Peptide Synthesis Specialty Synthesis Linear Core Amino Acids