Penicinoline
- CAS No.
- 1214268-60-6
- Chemical Name:
- Penicinoline
- Synonyms
- Penicinoline;1,4-dihydro-4-oxo-2-(1H-pyrrol-2-yl)-3-quinolinecarboxylic acid;3-Quinolinecarboxylic acid, 1,4-dihydro-4-oxo-2-(1H-pyrrol-2-yl)-
- CBNumber:
- CB86197900
- Molecular Formula:
- C14H10N2O3
- Molecular Weight:
- 254.24
- MDL Number:
- MFCD23133153
- MOL File:
- 1214268-60-6.mol
Penicinoline Chemical Properties,Uses,Production
Description
Penicinoline is an alkaloid that has been found in Penicillium and has antimalarial, insecticidal, and anticancer activities.1,2 It is active against chloroquine-sensitive and -resistant strains of P. falciparum (IC50 = 25 μM for both).1 Penicinoline (1,000 ppm) is also active against the aphid A. gossypii.2 It inhibits proliferation of 95-D and HepG2 cancer cells (IC50s = 0.57 and 6.5 μg/ml, respectively) but not HeLa, KB, KBv200, or Hep-2 cells (IC50s = >100 μg/ml).
References
1. Naveen, B., Ommi, N.B., Mudiraj, A., et al. Total synthesis of penicinoline E, marinamide, methyl marinamide and their antimalarial activity ChemistrySelect 2(11),3256-3261(2017).
2. Shao, C.-L., Wang, C.-Y., Gu, Y.-C., et al. Penicinoline, a new pyrrolyl 4-
Penicinoline Preparation Products And Raw materials
Raw materials
Preparation Products
Penicinoline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8864 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12007 | 58 |