Coenzyme A
- CAS No.
- 85-61-0
- Chemical Name:
- Coenzyme A
- Synonyms
- COA;COA-SH;COENZYME A HYDRATE;Lucina;Coalip;Aluzime;Thiol-CoA;SHUIRUJIE;COENZYME A;CONENZYME A
- CBNumber:
- CB8854470
- Molecular Formula:
- C21H36N7O16P3S
- Molecular Weight:
- 767.53
- MDL Number:
- MFCD06795839
- MOL File:
- 85-61-0.mol
- MSDS File:
- SDS
| Density | 1.96±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| solubility | PBS (pH 7.2): 10 mg/ml |
| form | A crystalline solid |
| pka | 9.6 (thiol); pK 6.4 (secondary phosphate); pK 4.0 (adenine NH3+) |
| Merck | 13,2491 |
| BRN | 77809 |
| LogP | -4.358 (est) |
| EWG's Food Scores | 1 |
| FDA UNII | SAA04E81UX |
| EPA Substance Registry System | Coenzyme A (85-61-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H315-H335 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 1-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2933299090 | |||||||||
| NFPA 704 |
|
Coenzyme A price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C4282 | Coenzyme A hydrate ≥85% (UV, HPLC) | 85-61-0 | 10mg | $81.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | C4282 | Coenzyme A hydrate ≥85% (UV, HPLC) | 85-61-0 | 25mg | $135 | 2024-03-01 | Buy |
| Alfa Aesar | J13787 | Coenzyme A trihydrate, free acid, Affymetrix/USB | 85-61-0 | 50mg | $108.19 | 2021-12-16 | Buy |
| Alfa Aesar | J13787 | Coenzyme A trihydrate, free acid, Affymetrix/USB | 85-61-0 | 1g | $1350.25 | 2021-12-16 | Buy |
| Cayman Chemical | 16147 | Coenzyme A ≥98% | 85-61-0 | 10mg | $74 | 2024-03-01 | Buy |
Coenzyme A Chemical Properties,Uses,Production
Description
Coenzyme A (CoA) is an essential cofactor functioning as an acyl group carrier and carbonyl-
Chemical Properties
yellowish lyophilisate
Uses
Coenzyme A hydrate has been used in the thiolase enzyme assay of recombinant acetoacetyl-CoA thiolase (rACAT) in Clonorchis sinensis. It may be used as a reference standard in Raman spectra measurements.
Uses
A hydrated form of Coenzyme A (CoA) is a useful biochemical research chemical, used in the preparation of high-yielding cell-free protein synthesis platforms.
Definition
ChEBI: Tetraanion of coenzyme A.
General Description
Coenzyme A is structurally composed of 2-aminoethanethiol, pantothenic acid and phosphorylated adenosine phosphate.
Biochem/physiol Actions
Coenzyme A is a cofactor involved in acyl group transfer. It is essential for carbohydrate, lipid and protein metabolism. Coenzyme A acts as a cofactor for vitamin B coenzymes.
Purification Methods
The white powder is best stored in an inert atmosphere in the dark in sealed ampoules after drying in vacuo over P2O5 at 34o. It has UV: max 259 nm ( 16,800) in H2O. [Buyske et al. J Am Chem Soc 76 3575 1954.] It is soluble in H2O but insoluble in EtOH, Et2O and M2CO. It is readily oxidised in air and is best kept as the more stable trilithium salt [Moffat & Khorana J Am Chem Soc 83 663 1961; see also Beinert et al. J Biol Chem 200 384 1953, De Vries et al. J Am Chem Soc 72 4838 1950, Gregory et al. J Am Chem Soc 74 854 1952 and Baddiley Adv Enzymol 16 1 1955]. [Beilstein 26 III/IV 3663.]
Coenzyme A Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 | info@binbobiological.com | China | 326 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| TopScience Biochemical | 00852-68527855 | info@itopbiochem.com | China Hong Kong | 902 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
View Lastest Price from Coenzyme A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-22 | Coenzyme A
85-61-0
|
US $0.00 / kg | 1kg | 99.8% | 1000 kg | BINBO BIOLOGICAL CO.,LTD | |
 |
2024-01-08 | Acetyl Coenzyme
85-61-0
|
US $50.00-30.00 / KG | 1KG | 99.50% | 20tons | Wuhan Boyuan Import & Export Co., LTD | |
 |
2024-01-08 | Coenzyme
85-61-0
|
US $20.00-12.00 / KG | 1KG | 99.50% | 20tons | Wuhan Boyuan Import & Export Co., LTD |
-
- Coenzyme A
85-61-0
- US $0.00 / kg
- 99.8%
- BINBO BIOLOGICAL CO.,LTD
-
- Acetyl Coenzyme
85-61-0
- US $50.00-30.00 / KG
- 99.50%
- Wuhan Boyuan Import & Export Co., LTD
-
- Coenzyme
85-61-0
- US $20.00-12.00 / KG
- 99.50%
- Wuhan Boyuan Import & Export Co., LTD