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siomycin A
- CAS No.
- 12656-09-6
- Chemical Name:
- siomycin A
- Synonyms
- siomycin A;Salomycin A;Mutabilycin;Mutabillicin;Antibiotic 6741-21;AKFVOKPQHFBYCA-OFENGFFDSA-N;Mutabilycin, SporangioMycin, 6741-21, Mutabillicin;Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-valyl-2,3-didehydroalanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexa...
- CBNumber:
- CB91371285
- Molecular Formula:
- C71H81N19O18S5
- Molecular Weight:
- 1648.84
- MDL Number:
- MOL File:
- 12656-09-6.mol
- MSDS File:
- SDS
Last updated:2023-05-18 11:31:10
| Density | 1.65±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | -20°C |
| solubility | DMSO: complete10 mg/ml, clear, colorless to faintly yellow |
| form | White solid. |
| pka | 10.43±0.46(Predicted) |
| FDA UNII | AJY431WN1J |
siomycin A price More Price(3)
siomycin A Chemical Properties,Uses,Production
Uses
Siomycin A is an antibiotic that inhibits FoxM1.
Uses
Siomycin is a macrocyclic antibiotic with potent and selective antibacterial activity discovered in 1969. Siomycin is a potent inhibitor of the oncogenic transcription factor, FoxM1. The reduced transcription activity is reflected in the down regulation of protein and mRNA levels of FoxM1 and effects on down stream genes, Cdc25B, survivin and CENPB. In vitro, siomycin inhibits FoxM1-induced cell growth on soft agar and selectively kill transformed but not normal cells.
siomycin A Preparation Products And Raw materials
Raw materials
Preparation Products
siomycin A Suppliers
Global( 45)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15396 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
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| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 | market@aladdin-e.com | China | 25014 | 65 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
12656-09-6(siomycin A)Related Search:
Antibiotic 6741-21
Mutabillicin
Mutabilycin
siomycin A
Mutabilycin, SporangioMycin, 6741-21, Mutabillicin
AKFVOKPQHFBYCA-OFENGFFDSA-N
Alaninamide, N-[(7R,8S)-2-carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-valyl-2,3-didehydroalanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexa...
Salomycin A
12656-09-6
C71H81N19O18S5