17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one

17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one structure

CAS No.: 4412-59-3

Chemical Name:: 17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one

Synonyms: Allisartan Isoproxil Impurity 35;17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one;17-Ethinyl-17-hy-droxy-18-methylestra-5(10),9(11)-dien-3-one;13-Ethyl-17-hydroxy-18,19-dinorpregna-5(10),9(11)-dien-20-ynone;(17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-5(10),9(11)-dien-20-yn-3-one;18,19-Dinorpregna-5(10),9(11)-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)-

CBNumber:: CB91451642

Molecular Formula:: C21H26O2

Molecular Weight:: 310.43

MDL Number:

MOL File:: 4412-59-3.mol

Last updated:2023-07-12 16:44:35

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17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one Properties

Boiling point	480.9±45.0 °C(Predicted)
Density	1.16±0.1 g/cm3(Predicted)
pka	12.99±0.40(Predicted)

17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one Chemical Properties,Uses,Production

Uses

(17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-5(10),9(11)-dien-20-yn-3-one is an intermediate in the synthesis of Gestrinone (G368800),which is a Steroidal antiestrogen, antiprogestogen, analog of Norgestrienone. Antigonadotropin.

17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one Preparation Products And Raw materials

Raw materials

1-Naphthol Acetylacetone Vinyl bromide

Preparation Products

13-Ethyl-17-hydroxy-18,19-dinorpregna-5(10),9(11)-dien-20-ynone 17-Ethinyl-17-hy-droxy-18-methylestra-5(10),9(11)-dien-3-one 17-Ethynyl-18-methylestra-5(10),9(11)-dien-17-ol-3-one 18,19-Dinorpregna-5(10),9(11)-dien-20-yn-3-one, 13-ethyl-17-hydroxy-, (17α)- (17α)-13-Ethyl-17-hydroxy-18,19-dinorpregna-5(10),9(11)-dien-20-yn-3-one Allisartan Isoproxil Impurity 35 4412-59-3