Brevilin A
- CAS No.
- 16503-32-5
- Chemical Name:
- Brevilin A
- Synonyms
- 6-OAP;Brevilin A;Brevelin A;brevillin A;6-O-Angeloylplenolin;(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a ,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (2Z)-2-methyl-2-bu tenoate;2-Butenoic acid,2-methyl-,(3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-ylester, (2Z)-
- CBNumber:
- CB92519594
- Molecular Formula:
- C20H26O5
- Molecular Weight:
- 346.42
- MDL Number:
- MFCD04034623
- MOL File:
- 16503-32-5.mol
| Boiling point | 494.0±45.0 °C(Predicted) |
|---|---|
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO:100.0(Max Conc. mg/mL);288.67(Max Conc. mM) |
| form | A solid |
| FDA UNII | EKT624Z4TZ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P280-P302+P352 |
Brevilin A price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL84204 | Brevilin A phyproof? Reference Substance | 16503-32-5 | 10MG | $629 | 2024-03-01 | Buy |
| ChemScene | CS-0023593 | Brevilin A 99.77% | 16503-32-5 | 5mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-0023593 | Brevilin A 99.77% | 16503-32-5 | 10mg | $430 | 2021-12-16 | Buy |
| Crysdot | CD32002260 | Brevilin A 95+% | 16503-32-5 | 5mg | $450 | 2021-12-16 | Buy |
| AvaChem | 4099 | Brevilin A | 16503-32-5 | 10mg | $490 | 2021-12-16 | Buy |
Brevilin A Chemical Properties,Uses,Production
Uses
Brevilin A can be used using a selective extraction method to obtain natural substances, and can also be applied to prepare derivatives to use for anti-cancer activity.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Enzyme inhibitor
This naturally occurring sesquiterpenoid (FW = 346.40 g/mol; CAS 16503- 32-5) from the volatile oils of the plant Centipeda minima inhibits (IC50 = 10 μg/mL) STAT3 phosphorylation in the Jak/STAT signal transduction pathway of A549R cells. Brevilin A showed high specificity on Janus Kinase activity and following STAT3 signaling without directly affecting some other signals, including p65, AKT and GSK-3β phosphorylation, as well as Src kinase activity. Brevilin A is also an antibiotic with activity against Giardia (IC50 = 16 μM) and Entamoeba histolitica (IC50 = 4–9 μM).
Brevilin A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Yongjian Pharmaceutical Co.,Ltd | +86-0523-80183620 +86-17701422015 | 982552664@qq.com | China | 258 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
View Lastest Price from Brevilin A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | Brevilin A
16503-32-5
|
US $0.00 / kg | 1kg | 98% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2020-02-11 | Brevilin A
16503-32-5
|
US $9.80 / KG | 1g | ＞98% | 20 tons | Career Henan Chemical Co |
-
- Brevilin A
16503-32-5
- US $0.00 / kg
- 98%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- Brevilin A
16503-32-5
- US $9.80 / KG
- ＞98%
- Career Henan Chemical Co