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4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline structure

CAS No.: 694499-26-8

Chemical Name:: 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline

Synonyms: PON50;SW-53;SWF-53;Ponatinib int2;Ponatinib Impurity 3;Pralsetinib Impurity 1;Intermediate of Ponatinib;4-(4-Methylpiperazinomethyl)-3-;4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline;4-(4-Methylpiperazinomethyl)-4-(trifluoromethyl)aniline

CBNumber:: CB92520701

Molecular Formula:: C13H18F3N3

Molecular Weight:: 273.3

MDL Number:: MFCD09909924

MOL File:: 694499-26-8.mol

MSDS File:: SDS

Last updated:2023-10-27 17:03:52

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4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Properties

Boiling point	329.1±42.0 °C(Predicted)
Density	1.227
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	7.55±0.10(Predicted)
InChI	InChI=1S/C13H18F3N3/c1-18-4-6-19(7-5-18)9-10-2-3-11(17)8-12(10)13(14,15)16/h2-3,8H,4-7,9,17H2,1H3
InChIKey	ZMWAZMYBMAAMAW-UHFFFAOYSA-N
SMILES	C1(N)=CC=C(CN2CCN(C)CC2)C(C(F)(F)F)=C1
FDA UNII	KFW56NE7FT

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H332-H315-H319-H335
Precautionary statements	P280
HS Code	2933599590

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M329373	4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline	694499-26-8	5g	$250	2021-12-16	Buy
Matrix Scientific	132323	4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline 97%	694499-26-8	25g	$2700	2021-12-16	Buy
Apolloscientific	PC51192	4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline 95+%	694499-26-8	1g	$17	2021-12-16	Buy
Oakwood	212607	4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline 95%	694499-26-8	1g	$19	2021-12-16	Buy
SynQuest Laboratories	3H30-3-3G	4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline 95.0%	694499-26-8	1g	$28	2021-12-16	Buy

Product number	Packaging	Price	Buy
M329373	5g	$250	Buy
132323	25g	$2700	Buy
PC51192	1g	$17	Buy
212607	1g	$19	Buy
3H30-3-3G	1g	$28	Buy

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Chemical Properties,Uses,Production

Uses

4-(6-Acryloyloxyhexyloxy)-benzoesure (4-cyanophenylester) can be used as an intermediate in organic synthesis, mainly used in laboratory research and development and in the process of chemical and pharmaceutical synthesis.

Synthesis

Synthesis_694499-26-8
4-((4-Methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline Into a solution 4-methyl-1-(4-nitro-2-(trifluoromethyl)benzyl)piperazine (1.5 g, 5 mmol) in MeOH (250 mL) was added Raney Nickel (0.15 g, 10 wt %). The suspension was stirred under hydrogen atmosphere (50 psi) for 24 hrs and monitored by TLC. The reaction mixture was filtered through celite and the filtrate was concentrated under reduced pressure to yield the desired product (1.36 g, 100%). 1H NMR (300 MHz, CDCl3) |?: 7.43-7.46 (1H, d, J=9.0 Hz), 6.91 (1H, s), 6.77-6.80 (1H, d J=9.0 Hz), 3.77 (2H, s), 3.54 (2H, s), 2.53 (8H, brs), 2.34 (3H, s).

storage

Store long-term at 2-8°C.

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline synthesis

Synthesis of 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline from Acetamide, 2,2,2-trifluoro-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

GZD 824 GZD856

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Suppliers

Global( 230)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
PharmOrgSyn Laboratories Co., Ltd.	+86-021-38228826 +86-13916602830	sales@pharmorgsyn.cn	China	140	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9341	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Shandonghaohong biotechnology Co.,ltd.	0635-6175299 13961496334	sale@inyelchem.com	CHINA	44	55
Anqing Chico Pharmaceutical Co., Ltd.	15380796838	chloewu@chicopharm.cn	CHINA	341	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	sales@dolonchem.com	CHINA	2972	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58

Supplier	Advantage
career henan chemical co	58
PharmOrgSyn Laboratories Co., Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Shandonghaohong biotechnology Co.,ltd.	55
Anqing Chico Pharmaceutical Co., Ltd.	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Accela ChemBio Inc.	58

View Lastest Price from 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-03-28	4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline 694499-26-8	US $0.00 / KG	25KG	98%	Inquiry	PNP Biotech Co. Ltd
2023-02-23	4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline 694499-26-8	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD
2021-07-06	4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline USP/EP/BP 694499-26-8	US $1.10 / g	1g	99.9%	100 Tons Min	Dideu Industries Group Limited

4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline
694499-26-8
US $0.00 / KG
98%
PNP Biotech Co. Ltd

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline
694499-26-8
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline USP/EP/BP
694499-26-8
US $1.10 / g
99.9%
Dideu Industries Group Limited

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline Spectrum

4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline(694499-26-8)¹HNMR

694499-26-8(4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline)Related Search:

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4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline 4-((4-Methylpiperazin-1-yl)methyl)-3-trifluoromethylphenylamine 4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline 4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)benzenamine BenzenaMine, 4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)- 4-[(4-Methyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)aniline 4-[(4-Methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)aniline 95+% 5-Amino-2-[(4-methylpiperazin-1-yl)methyl]benzotrifluoride, 1-[4-Amino-2-(trifluoromethyl)benzyl]-4-methylpiperazine 4-(4-Methylpiperazin-1-ylmethyl)-3-trifluoromethylaniline 4-((4-Methylpiperazin-1-yl)methyl)-3-trifluoromethylphenylamine Ponatinib Impurity 3 Ponatinib int2 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline IN Stock 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline IN Stock COA TDS free sample 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline TDS msds coa PON50 4-(4-METHYLPIPERAZINOMETHYL)-3-(TRIFLUOROMETHYL)ANILINE 694499-26-8 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline USP/EP/BP SWF-53 SW-53 Benzenamine, 4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoro... 3-(trifluoromethyl)-4-((4-methylpiperazin-1-yl)methyl)benzenamine 4-(4-Methylpiperazinomethyl)-3-(trifluoromethyl)aniline-d8 4-(4-Methylpiperazinomethyl)-4-(trifluoromethyl)aniline 1-[4-Amino-2-(Trifluoromethyl)benzyl]-4-MethylPiperazine 4-(4-Methylpiperazinomethyl)-3- Pralsetinib Impurity 1 Intermediate of Ponatinib 694499-26-8