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ChemicalBook >> CAS DataBase List >>(±)10-HDoHE

(±)10-HDoHE

(±)10-HDoHE Structure
(±)10-HDoHE structure
CAS No.
90780-50-0
Chemical Name:
(±)10-HDoHE
Synonyms
(±)10-HDHA;DDCYKEYDTGCKAS-SKSHMZPZSA-N;4,7,11,13,16,19-Docosahexaenoic acid, 10-hydroxy-, (4Z,7Z,11E,13Z,16Z,19Z)-
CBNumber:
CB92589777
Molecular Formula:
C22H32O3
Molecular Weight:
344.49
MDL Number:
MFCD08056081
MOL File:
90780-50-0.mol
Last updated:2023-06-08 09:03:02
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(±)10-HDoHE Properties

Boiling point 511.2±50.0 °C(Predicted)
Density 0.995±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
pka 4.58±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
NFPA 704
3
0 0

(±)10-HDoHE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 33400 (±)10-HDHA ≥98% 90780-50-0 25μg $77 2024-03-01 Buy
Cayman Chemical 33400 (±)10-HDHA ≥98% 90780-50-0 50μg $144 2024-03-01 Buy
Cayman Chemical 33400 (±)10-HDHA ≥98% 90780-50-0 100μg $273 2024-03-01 Buy
Cayman Chemical 33400 (±)10-HDHA ≥98% 90780-50-0 250μg $602 2024-03-01 Buy
Product number Packaging Price Buy
33400 25μg $77 Buy
33400 50μg $144 Buy
33400 100μg $273 Buy
33400 250μg $602 Buy

(±)10-HDoHE Chemical Properties,Uses,Production

Description

(±)10-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.1,2 It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes.3,4,5 (±)10-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

References

1. VanRollins, M., and Murphy, R.C. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate J. Lipid Res. 25(5),507-517(1984).
2. Reynaud, D., Thickitt, C.P., and Pace-Asciak, C.R. Facile preparation and structural determination of monohydroxy derivatives of docosahexaenoic acid (HDoHE) by α-tocopherol-directed autoxidation Anal. Biochem. 214(1),165-170(1993).
3. VanRollins, M., Baker, R.C., Sprecher, H., et al. Oxidation of docosahexaenoic acid by rat liver microsomes J. Biol. Chem. 259(9),5776-5783(1984).
4. Yamane, M., Abe, A., and Yamane, S. High-performance liquid chromatography-thermospray mass spectrometry of epoxy polyunsaturated fatty acids and epoxyhydroxy polyunsaturated fatty acids from an incubation mixture of rat tissue homogenate J. Chromatogr. 652(2),123-136(1994).
5. Kim, H.Y., Karanian, J.W., Shingu, T., et al. Sterochemical analysis of hydroxylated docosahexaenoates produced by human platelets and rat brain homogenate Prostaglandins 40(5),473-490(1990).

(±)10-HDoHE Preparation Products And Raw materials

Raw materials

Preparation Products

(±)10-HDoHE Suppliers

Global( 20)Suppliers
Supplier Tel Email Country ProdList Advantage
Alfa Chemistry 		+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Yichang Zhongyitai Trading Co., Ltd. 0717-6449896 13886658719 root@zhongyitai.com China 1977 58
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3004 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.com China 24246 58
Supplier Advantage
Alfa Chemistry 		58
Yichang Zhongyitai Trading Co., Ltd. 58
Alfa Chemistry 60
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
amyjetsci 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
(±)10-HDHA DDCYKEYDTGCKAS-SKSHMZPZSA-N 4,7,11,13,16,19-Docosahexaenoic acid, 10-hydroxy-, (4Z,7Z,11E,13Z,16Z,19Z)- 90780-50-0