ChemicalBook >> CAS DataBase List >>ABP688
ABP688
- CAS No.
- 924298-51-1
- Chemical Name:
- ABP688
- Synonyms
- ABP688;ABP 924298-51-1;3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime;3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime;2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime
- CBNumber:
- CB92669578
- Molecular Formula:
- C15H16N2O
- Molecular Weight:
- 240.3
- MDL Number:
- MFCD17018722
- MOL File:
- 924298-51-1.mol
Last updated:2023-09-04 15:51:00
| Boiling point | 361.4±52.0 °C(Predicted) |
|---|---|
| Density | 1.03±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 100 mM |
| form | A solid |
| pka | 2.78±0.19(Predicted) |
| FDA UNII | MV07K3XC4O |
ABP688 price More Price(3)
ABP688 Chemical Properties,Uses,Production
Uses
ABP 688 is a high affinity and selective of metabotropic glutamate receptor (mGluR5). Also, it inhibits glutamate induced calcium release from L(tk-) cells expressing human mGlu5 receptors.
Enzyme inhibitor
This high-affinity mGluR antagonist (FW = 240.31 g/mol; CAS 924298- 51-1; Soluble to 100 mM in DMSO; 50 mM in 1 eq. HCl), also named 3- [2-(6-methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime, targets the human metabolotrophic glutamate receptor-5 (mGluR5) (Ki = 1.7 nM) and inhibits glutamate-induced calcium release from Ltk-cells expressing human mGlu5 receptors (IC50 = 2.3 nM). Indeed, [11C]- ABP688 is a useful PET tracer for in vivo imaging of the mGluR5 in rodents.
storage
Store at -20°C
ABP688 Preparation Products And Raw materials
Raw materials
Preparation Products
ABP688 Suppliers
Global( 16)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 | klq@cw-bio.com | China | 3500 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 15221909166 | product02@bidepharm.com | China | 63720 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | market@aladdin-e.com | China | 48467 | 58 |
| United States Biological | -- | sales@advtechind.com | United States | 6106 | 58 |
ABP688
ABP 924298-51-1
3-[2-(6-Methyl-2-pyridinyl)ethynyl]-2-cyclohexene-1-one O-methyloxime
2-Cyclohexen-1-one, 3-[2-(6-methyl-2-pyridinyl)ethynyl]-, O-methyloxime
3-((6-Methylpyridin-2-yl)ethynyl)cyclohex-2-en-1-one O-methyl oxime
924298-51-1