GSK-LSD1
- CAS No.
- 1431368-48-7
- Chemical Name:
- GSK-LSD1
- Synonyms
- GSK-LSD1 2HCl;GSK-LSD;CS-1628;GSK-LSD1;GSK-LSD1 HC'k;GSKLSD1 GSK LSD1;GSK-LSD1 2hydrochloride;GSK-LSD1(LSD1inhibitor);GSK-LSD1 2HCl USP/EP/BP;GSK-LSD1 (trans-racemic)
- CBNumber:
- CB92738768
- Molecular Formula:
- C14H20N2
- Molecular Weight:
- 216.32
- MDL Number:
- MFCD28124398
- MOL File:
- 1431368-48-7.mol
GSK-LSD1 price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1072 | GSK-LSD1 ≥98% (HPLC) | 1431368-48-7 | 5mg | $115 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1072 | GSK-LSD1 ≥98% (HPLC) | 1431368-48-7 | 25mg | $462 | 2024-03-01 | Buy |
| Tocris | 5361 | GSKLSD1dihydrochloride ≥98%(HPLC) | 1431368-48-7 | 10 | $181 | 2021-12-16 | Buy |
| TRC | G797570 | GSKLSD1Dihydrochloride | 1431368-48-7 | 10mg | $125 | 2021-12-16 | Buy |
| TRC | G797570 | GSKLSD1Dihydrochloride | 1431368-48-7 | 5mg | $70 | 2021-12-16 | Buy |
GSK-LSD1 Chemical Properties,Uses,Production
Uses
GSK LSD1 Dihydrochloride is an irreversible mechanism-based inhibitor of LSD1. Lysine-specific demthylase 1 (LSD1) belonges to the flavin adenine dinucleotide (FAD) family-dependant amine oxidases that include MAOs and PAOs. Inhibits cell proliferation in cancer cell lines.
Uses
GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used as an inhibitor to study if the effect of phenelzine activation of human immunodeficiency virus (HIV) latency is caused due to LSD1.
Biochem/physiol Actions
GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns. For full characterization details, please visit the GSK-LSD1 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc
References
[1]. structural genomics consortium.http://www. thesgc.org/chemical-probes/lsd1.
GSK-LSD1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28200 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9425 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4604 | 58 |
