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2'-O,4'-C-Methylenecytidine

CAS No.
206055-69-8
Chemical Name:
2'-O,4'-C-Methylenecytidine
Synonyms
2'-O,4'-C-Methylenecytidine;2'-O,4'-C-Methylenecytidine;Cytidine, 2'-O,4'-C-methylene-;2’-O,4’-C-Methylenecytidine, LNA-C
CBNumber:
CB93334224
Molecular Formula:
C10H13N3O5
Molecular Weight:
255.23
MDL Number:
MFCD28342628
MOL File:
206055-69-8.mol
Last updated:2023-06-26 08:28:20

2'-O,4'-C-Methylenecytidine Properties

storage temp. Store at -20°C

2'-O,4'-C-Methylenecytidine Chemical Properties,Uses,Production

Biological Activity

2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands[1][2].

References

[1]. bicyclic nucleoside analogue, N-type conformation, synthesize oligonucleotides, duplexes [2]. Obika S, et, al. Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2′-O,4′-C-methyleneribonucleosides. Tetrahedron Letters. 1998 Jul 23; 39(30):5401-04.

293751-20-9
206055-69-8
Synthesis of 2'-O,4'-C-Methylenecytidine from 2(1H)?-?Pyrimidinone, 4-?amino-?1-?[2,?5-?anhydro-?4-?C-?[(benzoyloxy)?methyl]?-?3-?O-?(phenylmethyl)?-?α-?L-?lyxofuranosyl]?- (9CI)

2'-O,4'-C-Methylenecytidine Preparation Products And Raw materials

Raw materials

Preparation Products

2'-O,4'-C-Methylenecytidine Suppliers

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2'-O,4'-C-Methylenecytidine Cytidine, 2'-O,4'-C-methylene- 2’-O,4’-C-Methylenecytidine, LNA-C 2'-O,4'-C-Methylenecytidine 206055-69-8