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2-Phenylindole

2-Phenylindole structure

CAS No.: 948-65-2

Chemical Name:: 2-Phenylindole

Synonyms: 2-PHENYL-1H-INDOLE;1H-Indole,2-phenyl-;NSC 15776;stabilizeri;Stabilizer I;-Phenylindole;A-PHENYLINDOL;2-PHENYLINDOLE;a-Phenylindole;2-phenyl-indol

CBNumber:: CB9725557

Molecular Formula:: C14H11N

Molecular Weight:: 193.24

MDL Number:: MFCD00005608

MOL File:: 948-65-2.mol

MSDS File:: SDS

Last updated:2023-08-18 13:05:06

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2-Phenylindole Properties

Melting point	188-190 °C (lit.)
Boiling point	250 °C/10 mmHg (lit.)
Density	1.1061 (rough estimate)
refractive index	1.5850 (estimate)
Flash point	250°C/10mm
storage temp.	Sealed in dry,Room Temperature
solubility	almost transparency in Methanol
pka	16.80±0.30(Predicted)
form	Powder
color	Off-white to beige or slightly green
CAS DataBase Reference	948-65-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	MQD44HV3P1
NIST Chemistry Reference	1H-Indole, 2-phenyl-(948-65-2)
EPA Substance Registry System	1H-Indole, 2-phenyl- (948-65-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS07

Signal word

Danger

Hazard statements

H315-H318-H335-H413

Precautionary statements

P273-P280-P302+P352-P305+P351+P338+P310

Hazard Codes

Risk Statements

37/38-41

Safety Statements

26-39

WGK Germany

RTECS

NM1272500

TSCA

Yes

HS Code

29309090

NFPA 704


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2-Phenylindole price More Price(28)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P26600	2-Phenylindole technical grade, 95%	948-65-2	100g	$23.92	2024-03-01	Buy
Sigma-Aldrich	P26600	2-Phenylindole technical grade, 95%	948-65-2	5g	$36.4	2024-03-01	Buy
TCI Chemical	P0188	2-Phenylindole >98.0%(GC)	948-65-2	25g	$27	2024-03-01	Buy
TCI Chemical	P0188	2-Phenylindole >98.0%(GC)	948-65-2	250g	$78	2024-03-01	Buy
Alfa Aesar	B23674	2-Phenylindole, 95%	948-65-2	50g	$27.65	2024-03-01	Buy

Product number	Packaging	Price	Buy
P26600	100g	$23.92	Buy
P26600	5g	$36.4	Buy
P0188	25g	$27	Buy
P0188	250g	$78	Buy
B23674	50g	$27.65	Buy

2-Phenylindole Chemical Properties,Uses,Production

Chemical Properties

off-white to beige or slightly green powder

Uses

Reactant for preparation of:

Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition
Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
Organic light emitting diodes (OLEDs)
Anti inflammatory agents
Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors
Agents for cancer and malaria therapy
Antifungal and antibacterial agents
Fluorescent probes

Reactant in:

Difluorohydroxylation reactions?
Mannich-type reactions?

Uses

Phenylindole is a stabilizer in PVC-plastic products (α-phenylindole).

Uses

Reactant for preparation of: • ;Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Organic light emitting diodes (OLEDs)3• ;Anti inflammatory agents4• ;Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors5• ;Agents for cancer and malaria therapy6• ;Antifungal and antibacterial agents7• ;Fluorescent probes8Reactant in:• ;Difluorohydroxylation reactions†• ;Mannich-type reactions†

Preparation

2-phenylindole is prepared by condensing phenylhydrazine and acetophenone, and then closing the ring in the presence of zinc chloride. or it can be prepared by heating bromoacetophenone with excess aniline, or heating N-(2-methylphenyl)benzamide and sodium ethoxide at 360-380℃ in isolation from air.

Definition

ChEBI: 2-phenyl-1H-indole is a phenylindole.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 1459, 1992 DOI: 10.1016/S0040-4039(00)91646-0
Journal of Heterocyclic Chemistry, 29, p. 1085, 1992 DOI: 10.1002/jhet.5570290509

2-Phenylindole synthesis

Synthesis of 2-Phenylindole from Acetophenone and Phenylhydrazine

2-Phenylindole Preparation Products And Raw materials

Raw materials

Ethanol Biphenyl Acetone Acetophenone 2-Bromoacetophenone

Polyphosphoric acid Benzamide Acetic acid Phenylhydrazine 1-Propanone, 2,2-dimethyl-1-(2-phenyl-1H-indol-1-yl)-

N-[2-(cyanomethyl)phenyl]acetamide 2-(2-nitrophenyl)-1-phenylethanone 1-nitro-2-(2-phenylethenyl)benzene (E)-2-Nitrostilbene 2-phenylindoline

AcetaMide, 2,2,2-trifluoro-N-(2-iodophenyl)- 1-BROMO-2-PHENYLETHYNYL-BENZENE Phenylpropiolic acid

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Preparation Products

3-[(2,4-dihydro-2,4-dimethyl-3H-1,2,4-triazol-3-ylidene)hydrazono]-1-methyl-2-phenyl-3H-indolium chloride ACID RED 351

2-Phenylindole Suppliers

Global( 320)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12471	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21689	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8822	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hefei TNJ Chemical Industry Co.,Ltd.	55
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Accela ChemBio Inc.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Hubei xin bonus chemical co. LTD	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58

View Lastest Price from 2-Phenylindole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-18	2-Phenylindole 948-65-2	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-03-06	2-Phenylindole 948-65-2	US $5.00-2.00 / kg	1kg	99%	10000kg	Hebei Guanlang Biotechnology Co,.LTD
2023-02-25	2-Phenylindole 948-65-2	US $0.00 / KG	1KG	98%min	30tons/month	WUHAN FORTUNA CHEMICAL CO., LTD

2-Phenylindole
948-65-2
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

2-Phenylindole
948-65-2
US $5.00-2.00 / kg
99%
Hebei Guanlang Biotechnology Co,.LTD

2-Phenylindole
948-65-2
US $0.00 / KG
98%min
WUHAN FORTUNA CHEMICAL CO., LTD

2-Phenylindole Spectrum

2-Phenylindole(948-65-2)MS 2-Phenylindole(948-65-2)¹HNMR 2-Phenylindole(948-65-2)¹³CNMR 2-Phenylindole(948-65-2)IR1 2-Phenylindole(948-65-2)IR2 2-Phenylindole(948-65-2)Raman

948-65-2(2-Phenylindole)Related Search:

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1-PHENYL-2-PROPANOL Phenylacetone SODIUM 2-PHENYLINDOLE-5-SULFONATE,2-phenylindole-5-sulfonicacidsodiumsal BASIC RED 29 5-METHYL-2-PHENYLINDOLE

4',6-Diamidino-2-phenylindole dihydrochloride 2-(4-CHLOROPHENYL)INDOLE N-METHYL-2-PHENYLINDOLE,1-METHYL-2-PHENYLINDOLE 1-ETHYL-2-PHENYLINDOLE,N-ETHYL-2-PHENYLINDOLE 5,6-METHYLENEDIOXY-2-PHENYLINDOLE

N-Methyl-2-Phenylindole-3-Carboxaldehyde,1-METHYL-2-PHENYLINDOLE-3-CARBOXALDEHYDE,3-FORMYL-1-METHYL-2-PHENYLINDOLE,1-METHYL-2-PHENYLINDOLE-3-CARBOXYALDEHYDE 3-(4-Fluorophenyl)-1-isopropyl-1H-indole 1-Phenyloxindole

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2-phenyl-1h-indol 2-phenyl-indol a-Phenylindole 2-Phenylindole ,99% NSC 15776 2-Phenylindole technical grade, 95% PHENYLINDOL,ALPHA- 2-PHENYLINDOLE 2-PHENYLINDOLE, TECH., 95% 2-Phenylindole,95% alpha-Phenylindole Indole, 2-phenyl- -Phenylindole Stabilizer I stabilizeri ALPHA-PHENYLINDOL A-PHENYLINDOL 2-Phenylindole ISO 9001：2015 REACH 1H-Indole,2-phenyl- 2-PHENYL-1H-INDOLE 948-65-2 C6H5C8H6N C14H10KN Indoles Simple Indoles Heterocyclic Building Blocks Building Blocks Pyridines Building Blocks Heterocyclic Building Blocks intermediates Heterocycle-Indole series Building Blocks C13 to C27 Chemical Synthesis Heterocyclic Building Blocks Indoles Simple Indoles Heterocyclic Compounds Indole