グルカゴン様ペプチドI, ヒト
グルカゴン様ペプチドI, ヒト 物理性質
- 貯蔵温度 :
- −20°C
- 外見 :
- Solid
- 水溶解度 :
- Soluble to 5 mg/ml in water
- InChIKey:
- UKVFVQPAANCXIL-FJVFSOETSA-N
- CAS データベース:
- 87805-34-3
グルカゴン様ペプチドI, ヒト 価格
もっと(7)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01BCS4037542 |
GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat), H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp- |
87805-34-3 |
0.5mg |
￥95000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC1851 |
Glucagon-like peptide 1 (1-37) (human, rat) |
87805-34-3 |
1mg |
￥158000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01BCS4037542 |
GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat), H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp- |
87805-34-3 |
1mg |
￥152000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G3265 |
グルカゴン様ペプチドI, ヒト ≥97% (HPLC)
Glucagon-Like Peptide I human ≥97% (HPLC) |
87805-34-3 |
0.1mg |
￥37900 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G3265 |
グルカゴン様ペプチドI, ヒト ≥97% (HPLC)
Glucagon-Like Peptide I human ≥97% (HPLC) |
87805-34-3 |
0.5mg |
￥75300 |
2024-03-01 |
購入 |
グルカゴン様ペプチドI, ヒト 化学特性,用途語,生産方法
来歴
GLP-1 was first identified in the early 1980s, following the cloning of the proglucagon gene. The biological activity of GLP-1 was investigated initially by using the N-terminal extended forms of GLP-1(1–37 and 1–36 amide). However, these forms were devoid of biological activity. In the late 1980s, bioactive GLP-1 peptides were purified from gut extracts and were identified to be GLP1(7–37) and GLP-1(7–36)-amide. In the current literature, the unqualified designation of GLP-1 corresponds to the truncated peptides.
使用
Glucagon-Like Peptide I (GLP1) has been used as an antigen in excess amounts for the incubation of primary antibodies, post-immunocytochemistry with positive results of paraffin-embedded pancreatic tissues of
Rana temporaria.
一般的な説明
Glucagon-Like Peptide I (GLP1) is an incretin hormone, which functions as ligand for GLP1 receptors (GLP1R). These receptors are expressed in renal and cardiovascular system, such as smooth muscle and endothelial cells.
Biochem/physiol Actions
Glucagon-Like Peptide I (GLP1) controls the metabolism of glucose, by inducing the secretion of insulin and suppressing that of glucagon. Studies in Indonesian population show that reduced levels of this protein are linked with increased susceptibility to type 2 diabetes mellitus. Plasma levels of this hormone also show significant association with systolic and diastolic blood pressure levels.
副作用
Common side effects of GLP-1 include: loss of appetite, nausea, vomiting, diarrhoea. Other side effects may include: dizziness, mild tachycardia or increased heart rate, infection, headache, and indigestion. Temporary mild itching and redness of the skin at the injection site may also occur. Serious and rare side effects include: pancreatitis, medullary thyroid cancer, acute (sudden) kidney injury, worsening of diabetes-related retinopathy, and severe allergic reactions. And GLP-1 agonists are recommended during pregnancy because they can cause abnormal foetal development. Seek medical attention if any serious adverse reactions occur.
グルカゴン様ペプチドI, ヒト 上流と下流の製品情報
原材料
準備製品
グルカゴン様ペプチドI, ヒト 生産企業
Global( 126)Suppliers
87805-34-3(グルカゴン様ペプチドI, ヒト)キーワード:
- 87805-34-3
- HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY- THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARGY-GLY
- GLUCAGON-LIKE PEPTIDE I HUMAN
- GLUCAGON-LIKE PEPTIDE-1, HUMAN
- GLUCAGON-LIKE PEPTIDE I
- GLUCAGON-LIKE PEPTIDE 1 (1-37) (HUMAN)
- GLUCAGON-LIKE PEPTIDE 1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
- GLUCAGON-LIKE PEPTIDE 1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
- GLP-1
- GLP-1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
- GLP-1 (1-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
- GLP-1 (HUMAN)
- Glucagon-likepeptide1(1-37)
- glucagon-like peptide I (1-37)
- PREPROGLUCAGON 72-108
- PREPROGLUCAGON (92-128) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
- PROGLUCAGON (72-108) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT) TRIFLUOROACETATE SALT
- M.W. 4169.54 C186H275N51O59
- HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY
- Glucagon-like peptide 1 (1-37) (human, rat)
- GLP-1 (1-37) (huMan, bovine, guinea pig, Mouse, rat)
Preproglucagon (92-128) (huMan, bovine, guinea pig, Mouse, rat), Proglucagon (72-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (1-37) (huMan, bovine, guinea pig, Mouse, rat)
- Preproglucagon (92-128) (huMan, bovine, guinea pig, Mouse, rat), Proglucagon (72-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (1-37) (huMan, bovine, guinea pig, Mouse, rat)
- GLP-1 (1-37) (human, bovine, gp, mouse, rat)
- ANTI-GLP1 (CENTER) antibody produced in rabbit
- GATA-like protein 1
- H-HIS-ASP-GLU-PHE-GLU-ARG-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
- GLP-1 USP/EP/BP
- Rat GLP-I(1-37)
- GLP-1, 5mg/vial
- GLP-1 (1-37) (human)
- グルカゴン様ペプチドI, ヒト