2-methyloxan-4-one

 化学構造式
1193-20-0
CAS番号.
1193-20-0
化学名:
别名:
英語名:
2-methyloxan-4-one
英語别名:
2-methyltetrahydro-4H-pyran-4-one;2-Methyldihydro-2H-pyran-4(3H)-one;EOS-62013;2-Methyloxan-4-one;2-methyl-tetrahydropyran-4-one;tetrahydro-2-methyl-4H-Pyran-4-one;4H-Pyran-4-one, tetrahydro-2-methyl-;(RS)-2-methyl-tetrahydro-4H-pyran-4-one;2-methyl-tetrahydropyran-4-one ISO 9001:2015 REACH
CBNumber:
CB12501766
化学式:
C6H10O2
分子量:
114.14
MOL File:
1193-20-0.mol

2-methyloxan-4-one 物理性質

沸点 :
168-169 °C
比重(密度) :
1.0229 g/cm3
外見 :
liquid
色:
Clear, colourless
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
HSコード  2932990090
絵表示(GHS) GHS hazard pictograms
注意喚起語
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H315 皮膚刺激 皮膚腐食性/刺激性 2 警告 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 強い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 呼吸器への刺激のおそれ 特定標的臓器毒性、単回暴露; 気道刺激性 3 警告 GHS hazard pictograms
注意書き
P260 粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。
P280 保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。
P301+P312 飲み込んだ場合:気分が悪い時は医師に連絡する こと。

2-methyloxan-4-one 価格 もっと(14)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQE-0527
2-Methyl-tetrahydro-pyran-4-one
1193-20-0 100g ¥600000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01APOOR54543
2-Methyltetrahydro-4H-pyran-4-one
1193-20-0 250mg ¥8600 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01APOOR54543
2-Methyltetrahydro-4H-pyran-4-one
1193-20-0 1g ¥16800 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQE-0527
2-Methyl-tetrahydro-pyran-4-one
1193-20-0 1g ¥22500 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQE-0527
2-Methyl-tetrahydro-pyran-4-one
1193-20-0 5g ¥65000 2024-03-01 購入

2-methyloxan-4-one 化学特性,用途語,生産方法

製造方法

A solution of (2S)-2-methyltetrahydro-2H-pyran-4-ol (27.3 g, 235 mmol) in acetone (980 mL) was cooled in an ice bath and treated drop-wise with Jones reagent (2.5 M, 103 mL, 258 mmol). The reaction mixture was stirred for 10 minutes at 0 °C and then warmed to room temperature. After 30 minutes, the mixture was cooled to 0 °C. 2-Propanol (18 mL, 240 mmol) was added and stirred for 30 minutes. After the mixture had been concentrated in vacuo, the residue was partitioned between water and dichloromethane. The aqueous layer was extracted 3 times with dichloromethane, and the combined organic layers were dried over magnesium sulfate, filtered, and concentrated under reduced pressure to provide the product 2-methyloxan-4-one.
説明図

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 3494, 1994 DOI: 10.1021/jo00091a048

生物活性

2-methyloxan-4-one has been shown to affect cell function and signal transduction in various cell types. It has been reported to inhibit the growth of cancer cells and induce apoptosis, or programmed cell death. It has also been shown to inhibit the production of inflammatory cytokines and reduce inflammation in animal models. However, the potential therapeutic and toxic effects of 2-methyloxan-4-one in humans are not well studied and require further investigation.

2-methyloxan-4-one 上流と下流の製品情報

原材料

準備製品


2-methyloxan-4-one 生産企業

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  スペクトルデータ(1HNMR)


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