N-ピバロイル-L-チロシン 化学特性,用途語,生産方法
使用
N-Pivaloyl-L-tyrosine can be used in peptide N-terminal amino acid determination.
製造方法
Preparation of N-Pivaloyl-L-tyrosine Ethyl Ester
N-Pivaloyl-L-tyrosine could not be prepared from L-tyrosine following the previous method. Under the same conditions used for the preparation of IK, 90% of the starting material remained unreacted. N-Pivaloyl-L-tyrosine Ethyl Ester was, however, made from Ie by mild hydrolysis with dilute sodium hydroxide solution and subsequent esterification with absolute ethyl alcohol saturated with dry HCl gas. The material after chromatography on florisil was obtained as an oil. Comparison of the mobility with Ie on thin-layer chromatography in two solvent systems (I and 11) as well as conversion to Ie by further acylation confirmed the identity of the material.
N-ピバロイル-L-チロシン 上流と下流の製品情報
原材料
準備製品