rel-5β*-メチル-2α*-(1-メチルエチル)シクロヘキサノン 化学特性,用途語,生産方法
定義
本品は、次の化学式で表される有機化合物である。
化粧品の成分用途
皮膚保護剤
説明
Menthone has a characteristic odor similar to menthol. May be
prepared by oxidation of menthol.
化学的特性
Menthone has a characteristic mint-like odor.
天然物の起源
Reported found in severalstereoisomersin nature; l-menthone is a constituent of the essential oils of Russian and
American peppermint, geranium, Andropogon gragrans, Mentha timija and Mentha arvensis; d-menthone is present in the essential
oils of Barosma pulchellum, Nepeta japonica Maxim., and others. d-Isomenthone has been reported isolated from Micromeria abis sinica Benth., Pelargonium tomentosum Jacquin and others; l-isomenthone has been identified in Réunion geranium, Pelargonium
capitau and others. Also reported found in lemon peel oil, black currants, celery seed, cinnamon, peppermint, cornmint, pennyroyal
and other mentha oils, nutmeg, thymus, cocoa, mushrooms, starfruit, coriander leaf, rice, tarragon, calamus, buckwheat, sweet and
bitter fennel, cherimoya, buchu oil, clam and sweet grass oil.
使用
(±)-Menthone is a Menthol derivative. A volatile flavor compound found in human milk, red and black rice bran and specialty rice types.
製造方法
By oxidation of menthol.
安全性プロファイル
Moderately toxic by
ingestion, intravenous, and subcutaneous
routes. Mutation data reported. When
heated to decomposition it emits acrid
smoke and irritating fumes. See also
KETONES.
代謝
H?m?l?inen (1912) claimed that menthone was probably oxidized in the rabbit to ketomenthone, since the glucuronide produced was converted by warm dilute H
2SO
4 to a substance which was probably △
4(8 -p-menthen-3-one (pulegone). Williams (1940), however, showed that it underwent reduction in the rabbit with the production of d-neomenthol. The presence of l-menthol, the other possible reduction product, was not detected and it appeared that the biological reduction was asymmetric (Williams, 1959).
rel-5β*-メチル-2α*-(1-メチルエチル)シクロヘキサノン 上流と下流の製品情報
原材料
準備製品